Dimetacrine and its Impurities

Dimetacrine (brand names Istonil, Istonyl, Linostil, Miroistonil), also known as dimethacrine and acripramine, is a tricyclic antidepressant (TCA) used in Europe and formerly in Japan for the treatment of depression. Reference standards of Dimetacrine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.