A second-generation protease inhibitor, it is used for the treatment of HIV infections. It is administered along with ritonavir or cobicistat, to decrease metabolism and increase concentration.. Reference standards of Darunavir API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Darunavir
Catalogue No.:PA 04 06000
CAS :
Molecular Formula : C27H37N3O7S
Molecular Weight : 547.66
[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aminophenyl)sulfonyl]amino] propyl]carbamic Acid tert-Butyl Ester
Catalogue No.:PA 04 06510
Molecular Formula : C25H37N3O5S
Molecular Weight : 491.64
Darunavir O-β-D-Glucuronide
Catalogue No.:PA 04 06520
Molecular Formula : C33H45N3O13S
Molecular Weight : 723.79
(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl Acetate
Catalogue No.:PA 04 06530
Molecular Formula : C8H12O4
Molecular Weight : 172.18
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl-4-(N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylsulfamoyl)phenylcarbamate
Catalogue No.:PA 04 06540
[(3R,3aS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate
Catalogue No.:PA 04 06550
Molecular Formula : C11H13NO7
Molecular Weight : 271.22
(3aS,4S,6aR)-Tetrahydro-4-methoxyfuro[3,4-b]furan-2(3H)-one
Catalogue No.:PA 04 06560
Molecular Formula : C7H10O4
Molecular Weight : 158.15
Darunavir Diamino Impurity
Catalogue No.:PA 04 06570
Molecular Formula : C20H29N3O3S
Molecular Weight : 391.53
Darunavir Urea Impurity
Catalogue No.:PA 04 06580
Molecular Formula : C21H27N3O4S
Molecular Weight : 417.52
Darunavir Amine Dimer Impurity
Catalogue No.:PA 04 06590
Molecular Formula : C48H64N6O11S2
Molecular Weight : 965.19
Darunavir Furan Dimer Impurity
Catalogue No.:PA 04 06600
Molecular Formula : C34H45N3O11S
Molecular Weight : 703.8
Benzyl (2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydrxy-1-phenylbutan-2-yl)ureido)-N-isobutylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate
Catalogue No.:PA 04 06610
Molecular Formula : C43H58N6O9S2
Molecular Weight : 867.09
[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-Carbamic Acid Phenylmethyl Ester
Catalogue No.:PA 04 06620
Molecular Formula : C28H35N3O5S
Molecular Weight : 525.66
((2S,3R)-4-(4-(((((3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl)oxy)carbonyl)amino)-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamic Acid Phenylmethyl Ester
Catalogue No.:PA 04 06630
Molecular Formula : C35H43N3O9S
Molecular Weight : 681.8
(+)-Darunavir
Catalogue No.:PA 04 06640
Darunavir Ethanolate
Catalogue No.:PA 04 06650
Molecular Formula : C29H43N3O8S
Molecular Weight : 593.73
Darunavir Carbamic Acid Impurity
Catalogue No.:PA 04 06660
Molecular Formula : C21H29N3O5S
Molecular Weight : 435.54
4-Amino-N-(2-methylpropyl)-N-[[(4S,5R)-2-oxo-4-(phenylmethyl)-5-oxazolidinyl]methyl]-benzenesulfonamide
Catalogue No.:PA 04 06670
[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid Methyl Ester
Catalogue No.:PA 04 06680
Molecular Formula : C22H31N3O5S
Molecular Weight : 449.56
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)-1-isobutylureido)phenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 06690
(R)-Ethyl 3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-nitrobutanoate
Catalogue No.:PA 04 06700
Molecular Formula : C11H19NO6
Molecular Weight : 261.27
(3aR,4S,6aS)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one
Catalogue No.:PA 04 06710
(3aR,4R,6aS)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one
Catalogue No.:PA 04 06720
4-Amino-N-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide
Catalogue No.:PA 04 06730
4-Amino-N-((2S,3R)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide
Catalogue No.:PA 04 06740
4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-(isobutyl-d9)benzenesulfonamide
Catalogue No.:PA STI 005160
Molecular Formula : C20H20D9N3O3S
Molecular Weight : 400.58
Darunavir-d9
Catalogue No.:PA STI 024400
Molecular Formula : C27H28D9N3O7S
Molecular Weight : 556.72
4-Amino-N-((2R,3R)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide
Catalogue No.:PA 04 06790
2,5-Dioxopyrrolidin-1-yl ((3R,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) Carbonate
Catalogue No.:PA 04 06820
Molecular Weight : 271.23
Benzyl ((2S,3R)-4-((4-(3-((2S,3R)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)ureido)-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 06830
Molecular Formula : C49H62N6O9S2
Molecular Weight : 943.19
(3S,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol
Catalogue No.:PA 04 06840
Molecular Formula : C6H10O3
Molecular Weight : 130.14
(3R,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ol
Catalogue No.:PA 04 06850
(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ol
Catalogue No.:PA 04 06860
Hexahydrofuro[2,3-b]furan-3-ol
Catalogue No.:PA 04 06870
4-Amino-N-((2R,3S)-2-hydroxy-3-isocyanato-4-phenylbutyl)-N-isobutylbenzenesulfonamide
Catalogue No.:PA 04 0061000
(3aS,4R,6aR)-Tetrahydro-4-methoxyfuro[3,4-b]furan-2(3H)-one
Catalogue No.:PA 04 0061001
N-[(1R,2S)-2-Hydroxy-3-[(2-methylpropyl)[(4-nitrophenyl)sulfonyl]amino]-1-(phenylmethyl)propyl]carbamic Acid 1,1-Dimethylethyl Ester
Catalogue No.:PA 04 0061002
Molecular Formula : C25H35N3O7S
Molecular Weight : 521.63
(3R,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate compound with Ethanol (1:1)
Catalogue No.:PA 04 0061003
Molecular Weight : 593.74
(3S,3aR,6aS)-Darunavir Isomer
Catalogue No.:PA 04 0061004
Molecular Weight : 547.67
(3S,3aS,6aR)-Darunavir Isomer
Catalogue No.:PA 04 0061005
(3R,3aR,6aS)-Darunavir isomer
Catalogue No.:PA 04 0061006
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3S)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 06750
(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ylcarbonyl Darunavir
Catalogue No.:PA 04 06760
(2R,3S)-3-Amino-1-((4-amino-N-isobutylphenyl)sulfonamido)-4-phenylbutan-2-yl ((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl) Carbonate
Catalogue No.:PA 04 06770
(1R,2S)-Darunavir
Catalogue No.:PA 04 06780
(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl 4-Nitrophenyl Ester Carbonic Acid
Catalogue No.:PA 04 0061007
Molecular Formula : C13H13NO7
Molecular Weight : 295.25
N-[3-[[(4-aminophenyl)sulfonyl](2-hydroxy-2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic Acid Hexahydrofuro[2,3-b]furan-3-yl Ester
Catalogue No.:PA 04 0061008
Molecular Formula : C27H37N3O8S
Molecular Weight : 563.67
N-[(1S,2S)-2-Hydroxy-3-[(2-methylpropyl)[(4-nitrophenyl)sulfonyl]amino]-1-(phenylmethyl)propyl]carbamic Acid 1,1-Dimethylethyl Ester
Catalogue No.:PA 04 0061009
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-(((((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl)oxy)carbonyl)oxy)-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 0061010
Tert-butyl ((2S,3R)-4-(4-acetamido-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 0061011
Molecular Formula : C27H39N3O6S
Molecular Weight : 533.68
N-(4-(N-((2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl)-N-isobutylsulfamoyl)phenyl)acetamide
Catalogue No.:PA 04 0061012
Molecular Formula : C22H31N3O4S
Molecular Weight : 433.6
2,5-Dioxopyrrolidin-1-yl ((3S,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl) Carbonate
Catalogue No.:PA 04 0061013
N-((2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl)-n-isobutyl-4-nitrobenzene-1-sulfonamide Hydrochloride
Catalogue No.:PA 04 0061014
Molecular Formula : C20H28ClN3O5S
Molecular Weight : 457.97
4-Nitrobenzenesulfonyl chloride
Catalogue No.:PA 04 0061015
Molecular Formula : C6H4ClNO4S
Molecular Weight : 221.61
N-[(1S,2R)-2-Hydroxy-3-[(2-methylpropyl)[(4-nitrophenyl)sulfonyl]amino]-1-(phenylmethyl)propyl]carbamic acid (3r,3as,6ar)-hexahydrofuro[2,3-b]furan-3-yl ester
Catalogue No.:PA 04 0061016
Molecular Formula : C27H35N3O9S
Molecular Weight : 577.65
(3R,3aS,6aS)-Hexahydrofuro[2,3-b]furan-3-yl (4-(N-((2R,3S)-3-(((((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl)oxy)carbonyl)amino)-2-hydroxy-4-phenylbutyl)-N-isobutylsulfamoyl)phenyl)carbamate
Catalogue No.:PA 04 0061017
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-((4-amino-N-(2-hydroxy-2-methylpropyl)phenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 0061018
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-((4-amino-3-hydroxy-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 0061019
Benzyl ((2S,3R)-3-hydroxy-4-(isobutylamino)-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 0061020
Molecular Formula : C22H30N2O3
Molecular Weight : 370.49
(3S,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl (4-nitrophenyl) carbonate
Catalogue No.:PA 04 0061021
(3R,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl (4-nitrophenyl) carbonate
Catalogue No.:PA 04 0061022
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-3-hydroxy-4-((4-(isobutyl(methyl)amino)phenyl)sulfonamido)-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 0061023
Molecular Formula : C28H39N3O7S
Molecular Weight : 561.69
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-3-chloro-4-((4-(isobutylamino)phenyl)sulfonamido)-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 0061024
Molecular Formula : C27H36ClN3O6S
Molecular Weight : 566.11
1-epi-Darunavir
Catalogue No.:PA 04 0061026
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-((4-acetamido-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 0061027
Molecular Formula : C29H39N3O8S
Molecular Weight : 589.7
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl (4-nitrophenyl) carbonate
Catalogue No.:PA 04 0061028
2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) Carbonate
Catalogue No.:PA 04 0061025
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol
Catalogue No.:PA 04 0061029
tert-Butyl ((2S,3S)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 0061030
Molecular Weight : 491.65
tert-Butyl ((2R,3S)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 0061031
rel-(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl 4-nitrophenyl carbonate
Catalogue No.:PA 04 0061032
rel-Tert-butyl ((2R,3R)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
Catalogue No.:PA 04 0061033
[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](n-propyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic acid (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl- ester
Catalogue No.:PA 04 0061034
Molecular Formula : C26H35N3O7S
Molecular Weight : 533.64
Di-tert-butyl ((2S,2'S,3R,3'R)-(isobutylazanediyl)bis(3-hydroxy-1-phenylbutane-4,2-diyl))dicarbamate
Catalogue No.:PA 04 0061035
Molecular Formula : C34H53N3O6
Molecular Weight : 599.81
Tert-butyl ((2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl) carbamate
Catalogue No.:PA 04 0061036
Molecular Formula : C15H22ClNO3
Molecular Weight : 299.8
N-((2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-(methylamino)benzenesulfonamide
Catalogue No.:PA 04 0061037
Molecular Formula : C21H31N3O3S
Molecular Weight : 405.56
(2R,3S)-3-Amino-1-(isobutylamino)-4-phenylbutan-2-ol Hydrochloride
Catalogue No.:PA 04 0061038
Molecular Formula : C14H25ClN2O
Molecular Weight : 272.82
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