Darolutamide is used to treat certain types of prostate cancer that has not spread to other parts of the body in men who have not been helped by other medical treatments. It is sold under the brand name Nubeqa. Reference standards of Darolutamide API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Darolutamide
Catalogue No.:PA 04 1940000
CAS :
Molecular Formula : C19H19ClN6O2
Molecular Weight : 398.85
(S)-5-Acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide
Catalogue No.:PA 04 1941000
Molecular Formula : C19H17ClN6O2
Molecular Weight : 396.84
N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1-nitroso-1H-pyrazole-3-carboxamide
Catalogue No.:PA 04 1941001
Molecular Formula : C19H18ClN7O3
Molecular Weight : 427.85
2-Chloro-4-(1-nitroso-1H-pyrazol-3-yl)benzonitrile
Catalogue No.:PA 04 1941002
Molecular Formula : C10H5ClN4O
Molecular Weight : 232.63
(S)-5-Acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1-nitroso-1H-pyrazole-3-carboxamide
Catalogue No.:PA 04 1941003
Molecular Formula : C19H16ClN7O3
Molecular Weight : 425.83
N-Nitroso Darolutamide
Catalogue No.:PA 04 1941004
(E)-4,4'-(1,3-Dihydroxybut-1-ene-1,3-diyl)bis(2-chlorobenzonitrile)
Catalogue No.:PA 04 1941005
Molecular Formula : C18H12Cl2N2O2
Molecular Weight : 359.21
Darolutamide Pyrazol benzonitrile Impurity
Catalogue No.:PA 04 1941006
Molecular Formula : C10H6ClN3
Molecular Weight : 203.63
2-Methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline
Catalogue No.:PA 04 1941007
Molecular Formula : C10H12N4O
Molecular Weight : 204.23
N-((S)-1-(3-(4-Carbamoyl-3-chlorophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide
Catalogue No.:PA 04 1941008
Molecular Formula : C19H21ClN6O3
Molecular Weight : 416.87
Darolutamide Benzyl Amine
Catalogue No.:PA 04 1941009
Molecular Formula : C19H23ClN6O2
Molecular Weight : 402.88
N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl-2,3,3,3-d4)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide
Catalogue No.:PA STI 089899
Molecular Formula : C19H15D4ClN6O2
(S)-4-(1-(2-Aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile Hydrochloride
Catalogue No.:PA 04 1941011
Molecular Formula : C13H14Cl2N4
Molecular Weight : 297.18
3-Acetyl-1H-pyrazole-5-carboxylic Acid
Catalogue No.:PA 04 1941012
Molecular Formula : C6H6N2O3
Molecular Weight : 154.13
(S)-5-(1-Hydroxyethyl)-1H-pyrazole-3-carboxylic Acid
Catalogue No.:PA 04 1941013
Molecular Formula : C6H8N2O3
Molecular Weight : 156.14
4-Acetyl-2-chlorobenzonitrile
Catalogue No.:PA 04 1941014
Molecular Formula : C9H6ClNO
Molecular Weight : 179.6
tert-Butyl (S)-(1-hydroxypropan-2-yl)carbamate
Catalogue No.:PA 04 1941015
Molecular Formula : C8H17NO3
Molecular Weight : 175.23
Darolutamide R-Isomer
Catalogue No.:PA 04 1941016
2-Chloro-4-(1-((2S)-2-(5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamido)propyl)-1H-pyrazol-3-yl)benzoic Acid
Catalogue No.:PA 04 1941017
Molecular Formula : C19H20ClN5O4
Molecular Weight : 417.85
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