Dabrafenib is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. It is used alone or in combination with another medication to treat a type of skin cancer.. Reference standards of Dabrafenib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Dabrafenib
Catalogue No.:PA 31 06000
CAS :
Molecular Formula : C23H20F3N5O2S2
Molecular Weight : 519.56
3-Bromo-2-fluorobenzoic Acid
Catalogue No.:PA 31 06510
Molecular Formula : C7H4BrFO2
Molecular Weight : 219.01
Dabrafenib Mesylate
Catalogue No.:PA 31 06520
Molecular Formula : C24H24F3N5O5S3
Molecular Weight : 615.67
2,6-Difluorobenzenesulfonyl Chloride
Catalogue No.:PA 31 06530
Molecular Formula : C6H3ClF2O2S
Molecular Weight : 212.6
2,2-Dimethylthiopropionamide
Catalogue No.:PA 31 06540
Molecular Formula : C5H11NS
Molecular Weight : 117.21
2-Amino-N-(3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-6-fluorobenzenesulfonamide
Catalogue No.:PA 31 0061000
Molecular Formula : C23H22F2N6O2S2
Molecular Weight : 516.59
Carboxy Dabrafenib
Catalogue No.:PA 31 0061001
Molecular Formula : C23H18F3N5O4S2
Molecular Weight : 549.54
Hydroxy Dabrafenib
Catalogue No.:PA 31 0061002
Molecular Formula : C23H20F3N5O3S2
Molecular Weight : 535.56
Desmethyl Dabrafenib
Catalogue No.:PA 31 0061003
Molecular Formula : C22H18F3N5O2S2
Molecular Weight : 505.53
Dabrafenib-d9
Catalogue No.:PA STI 089392
Molecular Formula : C23H11D9F3N5O2S2
Molecular Weight : 528.62
2,4-Difluorobenzenesulfonyl Chloride
Catalogue No.:PA 31 0061004
Molecular Weight : 212.59
4-Bromo-2-fluorobenzenesulfonyl Chloride
Catalogue No.:PA 31 0061005
Molecular Formula : C6H3BrClFO2S
Molecular Weight : 273.5
2,4,6-Trifluorobenzene-1-sulfonyl Chloride
Catalogue No.:PA 31 0061006
Molecular Formula : C6H2ClF3O2S
Molecular Weight : 230.59
2-Fluoro-6-methoxybenzenesulphonyl Chloride
Catalogue No.:PA 31 0061007
Molecular Formula : C7H6ClFO3S
Molecular Weight : 224.63
Methyl 3-amino-4-fluorobenzoate
Catalogue No.:PA 31 0061008
Molecular Formula : C8H8FNO2
Molecular Weight : 169.16
Methyl 3-amino-5-fluorobenzoate
Catalogue No.:PA 31 0061009
Methyl 5-amino-2-fluorobenzoate
Catalogue No.:PA 31 0061010
3-Amino-2-fluorobenzoic Acid
Catalogue No.:PA 31 0061011
Molecular Formula : C7H6FNO2
Molecular Weight : 155.13
N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2-fluoro-6-methoxybenzenesulfonamide
Catalogue No.:PA 31 0061012
Molecular Formula : C24H23F2N5O3S2
Molecular Weight : 531.6
2-Fluoro-6-nitrobenzenesulfonyl Chloride
Catalogue No.:PA 31 0061013
Molecular Formula : C6H3ClFNO4S
Molecular Weight : 239.6
Methyl 3-amino-2-methoxybenzoate
Catalogue No.:PA 31 0061014
Molecular Formula : C9H11NO3
Molecular Weight : 181.19
N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)phenyl)-2,6-difluorobenzenesulfonamide
Catalogue No.:PA 31 0061015
Molecular Formula : C23H21F2N5O2S2
Molecular Weight : 501.57
N-(3-(2-(Tert-butyl)-5-(2-(dimethylamino)pyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
Catalogue No.:PA 31 0061016
Molecular Formula : C25H24F3N5O2S2
Molecular Weight : 547.62
M30-Dabrafenib
Catalogue No.:PA 31 0061017
Molecular Formula : C22H16F3N5O5S2
Molecular Weight : 551.52
M31-Dabrafenib
Catalogue No.:PA 31 0061018
Molecular Formula : C22H16F3N5O2S2
Molecular Weight : 503.52
Dabrafenib Glucuronide
Catalogue No.:PA 31 0061019
Molecular Formula : C28H24F3N5O9S2
Molecular Weight : 695.64
1-(2-chloropyrimidin-4-yl)-2-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)-2-oxoethyl 2,2-dimethylpropanimidothioate
Catalogue No.:PA 31 0061020
Molecular Formula : C23H20ClF3N4O3S2
Molecular Weight : 557
Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate
Catalogue No.:PA 31 0061021
Molecular Formula : C14H10F3NO4S
Molecular Weight : 345.29
N-(3-(2-(tert-Butyl)-5-(2-hydroxypyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
Catalogue No.:PA 31 0061022
Molecular Formula : C23H19F3N4O3S2
Molecular Weight : 520.55
2,6-Difluoro-N-(2-fluoro-3-(2-(2-hydroxypyrimidin-4-yl)acetyl)phenyl)benzenesulfonamide
Catalogue No.:PA 31 0061023
Molecular Formula : C18H12F3N3O4S
Molecular Weight : 423.37
2,6-Difluorobenzenesulfonyl Fluoride
Catalogue No.:PA 31 0061024
Molecular Formula : C6H3F3O2S
Molecular Weight : 196.14
N-(3-(2-(tert-Butyl)-4-hydroxy-5-(2-hydroxypyrimidin-4-yl)-4,5-dihydrothiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
Catalogue No.:PA 31 0061025
Molecular Formula : C23H21F3N4O4S2
Molecular Weight : 538.56
N-(3-(2-(Tert-butyl)-5-(2-chloropyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
Catalogue No.:PA 31 0061026
Molecular Formula : C23H18ClF3N4O2S2
Molecular Weight : 538.99
Methyl 2-fluoro-3-((2-fluoro-6-hydroxyphenyl)sulfonamido)benzoate
Catalogue No.:PA 31 0061027
Molecular Formula : C14H11F2NO5S
Molecular Weight : 343.3
Dabrafenib Amine Impurity
Catalogue No.:PA 31 0061028
Molecular Formula : C17H18FN5S
Molecular Weight : 343.42
N-(3-(2-(2-Aminopyrimidin-4-yl)acetyl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
Catalogue No.:PA 31 0061029
Molecular Formula : C18H13F3N4O3S
Molecular Weight : 422.38
Dabrafenib Diamine Sulfonamide Impurity
Catalogue No.:PA 31 0061030
5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)-4-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)thiazole 3-oxide
Catalogue No.:PA 31 0061031
2-Amino-4-(2-(tert-butyl)-4-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)thiazol-5-yl)pyrimidine 1-oxide
Catalogue No.:PA 31 0061032
Dabrafenib Methoxy Impurity
Catalogue No.:PA 31 0061033
Molecular Formula : C24H21F3N4O3S2
Molecular Weight : 534.57
Dabrafenib des-(tert-butyl)thiazol chloro impurity
Catalogue No.:PA 31 0061034
Molecular Formula : C18H11ClF3N3O3S
Molecular Weight : 441.81
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