Cyclandelate and its Impurities

Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis and Raynaud's disease. It is also used to treat nighttime leg cramps, and has been investigated for its effect against migraine. Reference standards of Cyclandelate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.