Crizotinib is used to treat certain types of lung cancer. It works by slowing or stopping the growth of lung cancer cells. It belongs to a class of drugs known as kinase inhibitors. Reference standards of Crizotinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Crizotinib-d5
Catalogue No.:PA STI 022770
CAS :
Molecular Formula : C21H17D5Cl2FN5O
Molecular Weight : 455.37
(R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)
Catalogue No.:PA STI 088317
Crizotinib
Catalogue No.:PA 03 3850000
Molecular Formula : C21H22Cl2FN5O
Molecular Weight : 450.34
2-Keto Crizotinib
Catalogue No.:PA 03 3851000
Molecular Formula : C21H20Cl2FN5O2
Molecular Weight : 464.32
(S)-Crizotinib
Catalogue No.:PA 03 3851001
(R,S)-Crizotinib
Catalogue No.:PA 03 3851002
(R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
Catalogue No.:PA 03 3851003
Molecular Formula : C13H10BrCl2FN2O
Molecular Weight : 380.04
(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-isopropylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
Catalogue No.:PA 03 3851004
Molecular Formula : C24H28Cl2FN5O
Molecular Weight : 492.42
(R)-4-(4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-yl)butan-1-ol
Catalogue No.:PA 03 3851005
Molecular Formula : C25H30Cl2FN5O2
Molecular Weight : 522.45
tert-Butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
Catalogue No.:PA 03 3851006
Molecular Formula : C26H30Cl2FN5O3
Molecular Weight : 550.46
Crizotinib Amine Impurity
Catalogue No.:PA 03 3851007
Molecular Formula : C13H11Cl2FN2O
Molecular Weight : 301.14
(R)-4-(4-(6-Amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-1-ol
Catalogue No.:PA 03 3851008
Molecular Formula : C21H22Cl2FN5O2
Molecular Weight : 466.34
(R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1H-pyrazol-4-yl)pyridin-2-amine
Catalogue No.:PA 03 3851009
Molecular Formula : C16H13Cl2FN4O
Molecular Weight : 367.21
tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
Catalogue No.:PA 03 3851010
Molecular Formula : C19H32BN3O4
Molecular Weight : 377.29
5-Bromo-2-nitropyridin-3-ol
Catalogue No.:PAI 03 385001
Molecular Formula : C5H3BrN2O3
Molecular Weight : 218.99
5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
Catalogue No.:PAI 03 385002
3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine
Catalogue No.:PAI 03 385003
Molecular Formula : C19H22BCl2FN2O3
Molecular Weight : 427.1
tert-Butyl 4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
Catalogue No.:PA 03 3851011
3-(1-(2-Chloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
Catalogue No.:PA 03 3851012
Molecular Formula : C21H23ClFN5O
Molecular Weight : 415.9
5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine
Catalogue No.:PAI 03 385004
Molecular Formula : C13H8BrCl2FN2O3
Molecular Weight : 410.02
(S)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-nitropyridine
Catalogue No.:PAI 03 385005
(S)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
Catalogue No.:PAI 03 385006
tert-Butyl (S)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
Catalogue No.:PAI 03 385007
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