Clozapine-impurities | Pharmaffiliates

clozapine and its Impurities

Clozapine is an atypical antipsychotic drug primarily used in people who are unresponsive to or intolerant to other antipsychotics.. Reference standards of Clozapine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 36 results for clozapine Impurities
PA 03 72000

Clozapine - API Standards

Clozapine


  • Catalogue No.:PA 03 72000

  • CAS :

    5786-21-0

  • Molecular Formula : C18H19ClN4

  • Molecular Weight : 326.83

PA 03 72010

Clozapine - Impurity A

8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one


  • Catalogue No.:PA 03 72010

  • CAS :

    50892-62-1

  • Molecular Formula : C13H9ClN2O

  • Molecular Weight : 244.68

PA 03 72020

Clozapine - Impurity B

11,11′-(Piperazine-1,4-diyl)bis(8-chloro-5H-dibenzo[b,e][1,4]diazepine)


  • Catalogue No.:PA 03 72020

  • CAS :

    263366-81-0

  • Molecular Formula : C30H24Cl2N6

  • Molecular Weight : 539.46

PA 03 72030

Clozapine - Impurity C (Freebase)

8-Chloro-11-(piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine


  • Catalogue No.:PA 03 72030

  • CAS :

    6104-71-8

  • Molecular Formula : C17H17ClN4

  • Molecular Weight : 312.8

PA 03 72040

Clozapine - Impurity D (Freebase)

1-[2-[(2-Amino-4-chlorophenyl)amino]benzoyl]-4-methylpiperazine


  • Catalogue No.:PA 03 72040

  • CAS :

    65514-71-8

  • Molecular Formula : C18H21ClN4O

  • Molecular Weight : 344.84

PA 03 72510

2-((4-Methylpiperazin-1-yl)methyl)benzonitrile

2-((4-Methylpiperazin-1-yl)methyl)benzonitrile


  • Catalogue No.:PA 03 72510

  • CAS :

    864069-00-1

  • Molecular Formula : C13H17N3

  • Molecular Weight : 215.29

PA 03 72520

3-((4-Methylpiperazin-1-yl)methyl)benzonitrile

3-((4-Methylpiperazin-1-yl)methyl)benzonitrile


  • Catalogue No.:PA 03 72520

  • CAS :

    859850-90-1

  • Molecular Formula : C13H17N3

  • Molecular Weight : 215.29

PA 03 72530

2,8-Dichloro-6,12-diphenylbenzo[c][1,5]benzodiazocine

2,8-Dichloro-6,12-diphenylbenzo[c][1,5]benzodiazocine


  • Catalogue No.:PA 03 72530

  • CAS :

    3646-61-5

  • Molecular Formula : C26H16Cl2N2

  • Molecular Weight : 427.32

PA STI 019920

4-(8-Chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)-1-piperazinecarboxylic Acid-d8 1,1-Dimethylethyl Ester

4-(8-Chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)-1-piperazinecarboxylic Acid-d8 1,1-Dimethylethyl Ester


  • Catalogue No.:PA STI 019920

  • CAS :

    2733718-84-6

  • Molecular Formula : C22H17D8ClN4O2

  • Molecular Weight : 420.96

PA STI 022360

Clozapine-d8

Clozapine-d8


  • Catalogue No.:PA STI 022360

  • CAS :

    1185053-50-2

  • Molecular Formula : C18H11D8ClN4

  • Molecular Weight : 334.87

PA STI 022370

Clozapine-d3

Clozapine-d3


  • Catalogue No.:PA STI 022370

  • CAS :

    1215691-72-7

  • Molecular Formula : C18H16D3ClN4

  • Molecular Weight : 329.84

PA STI 022371

Clozapine-d4

Clozapine-d4


  • Catalogue No.:PA STI 022371

  • CAS :

    204395-52-8

  • Molecular Formula : C18H15D4ClN4

  • Molecular Weight : 330.85

PA STI 028320

N-Desmethyl Clozapine-d8

N-Desmethyl Clozapine-d8


  • Catalogue No.:PA STI 028320

  • CAS :

    1189888-77-4

  • Molecular Formula : C17H9D8ClN4

  • Molecular Weight : 320.85

PA USP1142108

Clozapine Resolution Mixture (1142108)

Clozapine Resolution Mixture (1142108)


  • Catalogue No.:PA USP1142108

  • CAS :

    5786-21-0

  • Molecular Formula : NA

  • Molecular Weight : NA

PA BP905RB

clozapine (905RB)

clozapine (905RB)


  • Catalogue No.:PA BP905RB

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1142107

Clozapine (1142107)

Clozapine (1142107)


  • Catalogue No.:PA USP1142107

  • CAS :

    5786-21-0

  • Molecular Formula : NA

  • Molecular Weight : NA

PA EPC2460000

Clozapine (C2460000)

Clozapine (C2460000)


  • Catalogue No.:PA EPC2460000

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA EPY0000758

Clozapine for peak identification (Y0000758)

Clozapine for peak identification (Y0000758)


  • Catalogue No.:PA EPY0000758

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PAI 03 008020

8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine

8,11-Dichloro-5H-dibenzo[b,e][1,4]diazepine


  • Catalogue No.:PAI 03 008020

  • CAS :

    50373-22-3

  • Molecular Formula : C17H22N4O3S

  • Molecular Weight : 362.45

PA 03 72540

2-[(4-Chloro-2-nitrophenyl)amino]benzoic Acid

2-[(4-Chloro-2-nitrophenyl)amino]benzoic Acid


  • Catalogue No.:PA 03 72540

  • CAS :

    60091-87-4

  • Molecular Formula : C13H9ClN2O4

  • Molecular Weight : 292.68

PA 03 72550

Clozapine N-Oxide

Clozapine N-Oxide


  • Catalogue No.:PA 03 72550

  • CAS :

    34233-69-7

  • Molecular Formula : C18H19ClN4O

  • Molecular Weight : 342.83

PA IPIPRS 111 13

Clozapine (IPRS/111/13)-from IPC


  • Catalogue No.:PA IPIPRS 111 13

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA 03 72560

11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine

11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine


  • Catalogue No.:PA 03 72560

  • CAS :

    1977-07-7

  • Molecular Formula : C18H20N4

  • Molecular Weight : 292.39

PA 03 72570

2-((2-Amino-4-chlorophenyl)amino)benzoic Acid

2-((2-Amino-4-chlorophenyl)amino)benzoic Acid


  • Catalogue No.:PA 03 72570

  • CAS :

    67990-66-3

  • Molecular Formula : C13H11ClN2O2

  • Molecular Weight : 262.69

PA 03 0721000

Clozapine Resolution Mixture

Clozapine Resolution Mixture


  • Catalogue No.:PA 03 0721000

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA 03 0721001

2-((4-Chloro-2-nitrophenyl)amino)benzoyl chloride

2-((4-Chloro-2-nitrophenyl)amino)benzoyl chloride


  • Catalogue No.:PA 03 0721001

  • CAS :

    69414-55-7

  • Molecular Formula : C13H8Cl2N2O3

  • Molecular Weight : 311.12

PA 03 0721002

N-Acetyl clozapine

N-Acetyl clozapine


  • Catalogue No.:PA 03 0721002

  • CAS :

    1025951-76-1

  • Molecular Formula : C20H21ClN4O

  • Molecular Weight : 368.87

PA 03 0721003

8-Chloro-11-(4-nitrosopiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine

8-Chloro-11-(4-nitrosopiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine


  • Catalogue No.:PA 03 0721003

  • CAS :

    NA

  • Molecular Formula : C17H16ClN5O

  • Molecular Weight : 341.8

PA 03 0721004

N-Nitroso Clozapine

N-Nitroso Clozapine


  • Catalogue No.:PA 03 0721004

  • CAS :

    156632-03-0

  • Molecular Formula : C18H18ClN5O

  • Molecular Weight : 355.83

PA 03 0721005

8-Chloro-11-(4-nitrosopiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine 2,2,2-Trifluoroacetate

8-Chloro-11-(4-nitrosopiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine 2,2,2-Trifluoroacetate


  • Catalogue No.:PA 03 0721005

  • CAS :

    NA

  • Molecular Formula : C19H17ClF3N5O3

  • Molecular Weight : 455.82

PA 03 0721006

(3aR,11aS)-5-(6-(4-Acryloylpiperazin-1-yl)pyridin-2-yl)-6-fluoro-10-methyl-1-(6-methyl-4-(trifluoromethyl)pyridin-2-yl)-1,3a,4,5,10,11a-hexahydro-2H-benzo[b]pyrrolo[2,3-f][1,4]diazocine-2,11(3H)-dione

(3aR,11aS)-5-(6-(4-Acryloylpiperazin-1-yl)pyridin-2-yl)-6-fluoro-10-methyl-1-(6-methyl-4-(trifluoromethyl)pyridin-2-yl)-1,3a,4,5,10,11a-hexahydro-2H-benzo[b]pyrrolo[2,3-f][1,4]diazocine-2,11(3H)-dione


  • Catalogue No.:PA 03 0721006

  • CAS :

    2924015-21-2

  • Molecular Formula : C32H31F4N7O3

  • Molecular Weight : 637.64

PA 03 0721007

(3aR,11aS)-5-((2-(4-Acryloylpiperazin-1-yl)oxazol-4-yl)methyl)-6-fluoro-10-methyl-1-(6-methyl-4-(trifluoromethyl)pyridin-2-yl)-1,3a,4,5,10,11a-hexahydro-2H-benzo[b]pyrrolo[2,3-f][1,4]diazocine-2,11(3H)-dione

(3aR,11aS)-5-((2-(4-Acryloylpiperazin-1-yl)oxazol-4-yl)methyl)-6-fluoro-10-methyl-1-(6-methyl-4-(trifluoromethyl)pyridin-2-yl)-1,3a,4,5,10,11a-hexahydro-2H-benzo[b]pyrrolo[2,3-f][1,4]diazocine-2,11(3H)-dione


  • Catalogue No.:PA 03 0721007

  • CAS :

    2924016-00-0

  • Molecular Formula : C31H31F4N7O4

  • Molecular Weight : 641.63

PA 03 0721008

8-Chloro-5-nitroso-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one

8-Chloro-5-nitroso-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one


  • Catalogue No.:PA 03 0721008

  • CAS :

    90353-66-5

  • Molecular Formula : C13H8ClN3O2

  • Molecular Weight : 273.68

PA 03 0721009

8-Chloro-11-(4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazin-1-yl)-5-nitroso-5H-dibenzo[b,e][1,4]diazepine

8-Chloro-11-(4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazin-1-yl)-5-nitroso-5H-dibenzo[b,e][1,4]diazepine


  • Catalogue No.:PA 03 0721009

  • CAS :

    NA

  • Molecular Formula : C30H23Cl2N7O

  • Molecular Weight : 568.46

PA 03 0721010

N-(2-Amino-4-chlorophenyl)-N-(2-(4-methylpiperazine-1-carbonyl)phenyl)nitrous amide

N-(2-Amino-4-chlorophenyl)-N-(2-(4-methylpiperazine-1-carbonyl)phenyl)nitrous amide


  • Catalogue No.:PA 03 0721010

  • CAS :

    NA

  • Molecular Formula : C18H20ClN5O2

  • Molecular Weight : 373.84

PA 03 0721011

1,4-bis(8-Chloro-5-nitroso-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazine

1,4-bis(8-Chloro-5-nitroso-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazine


  • Catalogue No.:PA 03 0721011

  • CAS :

    NA

  • Molecular Formula : C30H22Cl2N8O2

  • Molecular Weight : 597.46