Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration. It is a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process.. Reference standards of Clarithromycin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Clarithromycin
Catalogue No.:PA 03 60000
CAS :
Molecular Formula : C38H69NO13
Molecular Weight : 747.95
6-O-Methyl-15-norerythromycin A
Catalogue No.:PA 03 60020
Molecular Formula : C37H67NO13
Molecular Weight : 733.93
6-O-Methylerythromycin A (E)-9-oxime
Catalogue No.:PA 03 60030
Molecular Formula : C38H70N2O13
Molecular Weight : 762.97
3″-N-Demethyl-6-O-methylerythromycin A
Catalogue No.:PA 03 60040
6,11-di-O-methylerythromycin A
Catalogue No.:PA 03 60050
Molecular Formula : C39H71NO13
Molecular Weight : 761.98
6-O-Methylerythromycin A (E)-9-(O-methyloxime)
Catalogue No.:PA 03 60070
Molecular Formula : C39H72N2O13
Molecular Weight : 776.99
3″-N-demethyl-3′-N-formyl-6-O-methylerythromycin A
Catalogue No.:PA 03 60080
Molecular Formula : C38H67NO14
Molecular Weight : 761.94
3-O-Decladinosyl-6-O-methylerythromycin A
Catalogue No.:PA 03 60090
Molecular Formula : C30H55NO10
Molecular Weight : 589.76
Erythromycin A (E)-9-oxime
Catalogue No.:PA 03 60100
Molecular Formula : C37H68N2O13
Molecular Weight : 748.94
3-O-Decladinosyl-8,9:10,11-dianhydro-6-O-methylerythromycin A-9,12-hemiketal
Catalogue No.:PA 03 60110
Molecular Formula : C30H51NO8
Molecular Weight : 553.73
6-O-Methylerythromycin A (Z)-9-oxime
Catalogue No.:PA 03 60120
3''-N-Demethyl-6-O-methylerythromycin A (E)-9-oxime
Catalogue No.:PA 03 60130
(10E)-10,11-Didehydro-11-deoxy-6-O-methylerythromycin A
Catalogue No.:PA 03 60140
Molecular Formula : C38H67NO12
Molecular Weight : 729.94
6-O-Methylerythromycin A (Z)-9-(O-methyloxime)
Catalogue No.:PA 03 60150
N-Demethyl Erythromycin A
Catalogue No.:PA 03 60510
Molecular Formula : C36H65NO13
Molecular Weight : 719.9
Clarithromycin N-oxide
Catalogue No.:PA 03 60560
Molecular Formula : C38H69NO14
Molecular Weight : 763.95
N-Nitroso-N-Desmethyl-Clarithromycin
Catalogue No.:PA 03 0601010
Molecular Formula : C37H66N2O14
Molecular Weight : 762.94
Clarithromycin F
Catalogue No.:PA 03 60010
6,12-Di-O-Methylerythromycin A
Catalogue No.:PA 03 60060
4′,6-Di-O-methylerythromycin A
Catalogue No.:PA 03 60160
6-O-Methylerythromycin A 9-(E)-O-(1-isopropoxycyclohexyl)-oxime
Catalogue No.:PA 03 60520
Molecular Formula : C47H86N2O14
Molecular Weight : 903.19
9-Ketal Oxime Clarithromycin
Catalogue No.:PA 03 60530
Molecular Formula : C42H78N2O14
Molecular Weight : 835.07
Clarithromycin KLN-6
Catalogue No.:PA 03 60540
Molecular Formula : C41H76N2O14
Molecular Weight : 821.05
Clarithromycin Lactobionate
Catalogue No.:PA 03 60550
Molecular Formula : C50H91NO25
Molecular Weight : 1106.25
Clarithromycin-N-methyl-d3
Catalogue No.:PA STI 021830
Molecular Formula : C38H66D3NO13
Molecular Weight : 750.97
Clarithromycin 13C D3
Catalogue No.:PA STI 021831
Molecular Formula : C3713CH66D3NO13
Molecular Weight : 751.96
Clarithromycin (1134379)
Catalogue No.:PA USP1134379
Molecular Formula : NA
Molecular Weight : NA
clarithromycin (833RB)
Catalogue No.:PA BP833RB
clarithromycin impurity E (834RB)
Catalogue No.:PA BP834RB
Clarithromycin for peak identification (Y0000321)
Catalogue No.:PA EPY0000321
Clarithromycin Related Compound A (6,11-di-O-methylerythromycin A) (1134380)
Catalogue No.:PA USP1134380
Clarithromycin Impurity D (N-desmethyl clarithromycin) (1134619)
Catalogue No.:PA USP1134619
Clarithromycin Impurity Q (N-oxide clarithromycin) (1134631)
Catalogue No.:PA USP1134631
Clarithromycin Impurity H (N-formyl clarithromycin) (1134620)
Catalogue No.:PA USP1134620
Clarithromycin Identity (1134390)
Catalogue No.:PA USP1134390
Clarithromycin Impurity R (N-desmethyl erythromycin A) (1134642)
Catalogue No.:PA USP1134642
Clarithromycin (Y0000320)
Catalogue No.:PA EPY0000320
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-10-(methoxyimino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
Catalogue No.:PA 03 60570
Molecular Weight : 777.01
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-12,13-dihydroxy-4-(((2R,4R,5R,6R)-5-hydroxy-4,6-dimethoxy-4-methyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13,14-heptamethyloxacyclotetradecane-2,10-dione
Catalogue No.:PA 03 60580
Molecular Formula : C37H67NO14
Molecular Weight : 749.94
Catalogue No.:PA IPIPRS 30 14
Molecular Formula :
Clarithromycin 9-Oxime
Catalogue No.:PA 03 60590
Molecular Weight : 762.98
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-7-ethoxy-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-10-(((2-methoxypropan-2-yl)oxy)imino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
Catalogue No.:PA 03 60600
Molecular Formula : C49H96N2O14Si2
Molecular Weight : 993.48
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10-(((2-ethoxypropan-2-yl)oxy)imino)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
Catalogue No.:PA 03 60610
Molecular Weight : 835.09
(3R,4S,5S,6R,9R,11S,12R,13S,14R,E)-6-(((2S,4S,6S)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
Catalogue No.:PAI 03 034010
(3R,4S,5S,6R,9R,11S,12R,13S,14R,E)-6-(((2S,4S,6S)-4-(Dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-7-methoxy-4-(((2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-10-(((2-methoxypropan-2-yl)oxy)imino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
Catalogue No.:PAI 03 034020
Molecular Formula : C48H94N2O14Si2
Molecular Weight : 979.45
(3R,4S,5S,6R,9R,11S,12R,13S,14R,E)-4-(((2R,4R,5S,6S)-4,5-Dimethoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,4S,6S)-4-(dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-7-methoxy-10-(((2-methoxypropan-2-yl)oxy)imino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
Catalogue No.:PAI 03 034030
Molecular Formula : C46H88N2O14Si
Molecular Weight : 921.30
(3R,4S,5S,6R,9R,11S,12R,13S,14R,E)-4-(((2R,4R,5S,6S)-4,5-Dimethoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,4S,6S)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
Catalogue No.:PAI 03 034040
(3R,4S,5S,6R,9R,11S,12R,13S,14R,Z)-14-Ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,4S,6S)-3-hydroxy-6-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
Catalogue No.:PAI 03 034050
Molecular Weight : 748.95
14-Hydroxy Clarithromycin
Catalogue No.:PA 03 0601000
Molecular Weight : 763.96
Clarithromycin Identity
Catalogue No.:PA 03 0601001
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-Ethyl-4,6,12,13-tetrahydroxy-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
Catalogue No.:PA 03 0601002
Molecular Formula : C22H40O8
Molecular Weight : 432.55
8a-Aza-8a-homoerythromycin A
Catalogue No.:PA 03 0601003
(2S,3R,4S,6R)-2-(((2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-15-oxo-7-propyl-1-oxa-7-azacyclopentadecan-11-yl)oxy)-3-hydroxy-N,N,6-trimethyltetrahydro-2H-pyran-4-amine oxide
Catalogue No.:PA 03 0601004
Molecular Formula : C40H76N2O13
Molecular Weight : 793.05
N-Despropyl gamithromycin
Catalogue No.:PA 03 0601005
Molecular Formula : C37H70N2O12
Molecular Weight : 734.97
(2R,3S,6R,8R,9R,10S,11S,12R)-2-((3R)-2,3-Dihydroxypentan-2-yl)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-hydroxy-11-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,6,8,10,12-pentamethyl-5-propyl-1-oxa-5-azacyclotridecan-13-one
Catalogue No.:PA 03 0601006
Molecular Formula : C40H76N2O12
Molecular Weight : 777.05
(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10,13-tetrahydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-1-oxa-7-azacyclopentadecan-15-one;
Catalogue No.:PA 03 0601007
Molecular Formula : C32H62N2O9
Molecular Weight : 618.85
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-6-propyl-1-oxa-6-azacyclopentadecan-15-one
Catalogue No.:PA 03 0601008
(14R)-14-Hydroxy Clarithromycin
Catalogue No.:PA 03 0601009
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-7-methoxy-4-(((2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
Catalogue No.:PAI 03 034051
Molecular Formula : C44H85NO13Si2
Molecular Weight : 892.33
(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-7,12-dimethoxy-4-(((2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
Catalogue No.:PAI 03 034052
Molecular Formula : C45H87NO13Si2
Molecular Weight : 906.36
Boron Complex of 2',4"-O-Bis(trimethylsilyl)-9(S)-9-dihydroClarithromycin
Catalogue No.:PAI 03 034056
Molecular Formula : C88H170BN2NaO26Si4
Molecular Weight : 1818.46
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12-hydroxy-7,13-dimethoxy-4-(((2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
Catalogue No.:PAI 03 034055
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-10,12-dihydroxy-7,13-dimethoxy-4-(((2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
Catalogue No.:PAI 03 034054
Molecular Formula : C45H89NO13Si2
Molecular Weight : 908.37
6,4"-Di-O-methylerythromycin A 9-oxime
Catalogue No.:PAI 03 034059
2'-O-TMS-6,4"-Di-O-methylerythromycin A 9-[(1-ethoxy-1-methylethyl)-oxime]
Catalogue No.:PAI 03 034058
Molecular Formula : C47H90N2O14Si
Molecular Weight : 935.32
6-O-Methyl-2'-O-(trimethylsilyl)-9-[O-(1-ethoxy-1-methylethyl)oxime] Erythromycin
Catalogue No.:PAI 03 034057
Molecular Weight : 921.3
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-(((2R,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
Catalogue No.:PA 03 0601011
Molecular Weight : 733.94
(2S,4R,4a'R,5S,6S,7'R,8'S,9'R,10'R,12'R,14'R,15'R,16'S,16a'S)-15'-(((3S,4S,6S)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-7'-ethyl-5,8',9'-trihydroxy-4,14'-dimethoxy-4,6,8',10',12',14',16'-heptamethylhexadecahydro-5'H,11'H-spiro[pyran-2,2'-[1,3]dioxino[5,4-c][1]oxacyclotetradecine]-5',11'-dione
Catalogue No.:PA 03 0601012
Molecular Weight : 761.95
6-O-Methylerythromycin B
Catalogue No.:PA 03 0601013
Molecular Formula : C38H69NO12
Molecular Weight : 731.97
Clarithromycin (IPRSC030)
Catalogue No.:PA IPRSC030
Clarithromycin Hydrazone
Catalogue No.:PAI 03 034060
Molecular Formula : C38H71N3O12
Molecular Weight : 762
(14S)-14-Hydroxy Clarithromycin
Catalogue No.:PA 03 0601014
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