Cevimeline is used in the treatment of dry mouth and especially associated with Sjögren's syndrome. It is a parasympathomimetic and muscarinic agonist, with particular effect on M1 and M3 receptors.. Reference standards of Cevimeline API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Cevimeline
Catalogue No.:PA 56 31000
CAS :
Molecular Formula : C10H17NOS
Molecular Weight : 199.30
Cevimeline-d4 Hydrochloride Salt
Catalogue No.:PA STI 018790
Molecular Formula : C10H14D4ClNOS
Molecular Weight : 239.8
Cevimeline Thiol Impurity
Catalogue No.:PA 56 0311000
Molecular Formula : C8H15NOS
Molecular Weight : 173.27
(2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide
Catalogue No.:PA 56 0311001
Molecular Formula : C10H17NO2S
Molecular Weight : 215.31
Cevimeline Diol
Catalogue No.:PA 56 0311002
Molecular Formula : C8H15NO2
Molecular Weight : 157.21
Cevimeline trans-Isomer Dihydrochloride Monohydrate
Catalogue No.:PA 56 0311003
Molecular Formula : C20H38Cl2N2O3S2
Molecular Weight : 489.56
(E)-1,4'-Diaza[2,2'-bi(bicyclo[2.2.2]octanylidene)]-3-one--(Z)-1,4'-diaza[2,2'-bi(bicyclo[2.2.2]octanylidene)]-3-one (1/1)
Catalogue No.:PA 56 0311004
Molecular Formula : C14H20N2O
Molecular Weight : 232.3
3,3'-(Thiobis(methylene))bis(quinuclidin-3-ol)
Catalogue No.:PA 56 0311005
Molecular Formula : C16H28N2O2S
Molecular Weight : 312.47
3,3'-(Disulfanediylbis(methylene))bis(quinuclidin-3-ol)
Catalogue No.:PA 56 0311006
Molecular Formula : C16H28N2O2S2
Molecular Weight : 344.53
(2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3',3'-dioxide
Catalogue No.:PA 56 0311007
Molecular Formula : C10H17NO3S
Molecular Weight : 231.31
(Disulfanediylbis(methylene))bis(quinuclidine-3,3-diyl) Diacetate
Catalogue No.:PA 56 0311008
Molecular Formula : C20H32N2O4S2
Molecular Weight : 428.61
3-((((3-Hydroxyquinuclidin-3-yl)methyl)disulfanyl)methyl)quinuclidin-3-yl Acetate
Catalogue No.:PA 56 0311009
Molecular Formula : C18H30N2O3S2
Molecular Weight : 386.57
3,3'-((Ethane-1,1-diylbis(sulfanediyl))bis(methylene))bis(quinuclidin-3-ol)
Catalogue No.:PA 56 0311010
Molecular Formula : C18H32N2O2S2
Molecular Weight : 372.59
Cevimeline trans-Isomer
Catalogue No.:PA 56 0311011
Molecular Weight : 199.31
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