Cabozantinib Fumarate and its Impurities

Cabozantinib Fumarate is a tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer. Reference standards of Cabozantinib Fumarate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.