Cabotegravir is also known as S/GSK1265744 or GSK744. It is an analog of dolutegravir, prevents viral DNA integration into the host genome and inhibits HIV replication. Reference standards of Cabotegravir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Cabotegravir
Catalogue No.:PA 03 3510000
CAS :
Molecular Formula : C19H17F2N3O5
Molecular Weight : 405.36
(3S,11aR)-N-(2,4-Difluorobenzyl)-3-methyl-5,7-dioxo-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
Catalogue No.:PA 03 3511001
Molecular Formula : C25H27F2N3O10
Molecular Weight : 567.5
Cabotegravir O-Beta-D-Glucuronide
Catalogue No.:PA 03 3511000
Molecular Formula : C25H25F2N3O11
Molecular Weight : 581.48
Cabotegravir RR Isomer
Catalogue No.:PA 03 3511002
Cabotegravir RS isomer
Catalogue No.:PA 03 3511003
Cabotegravir SS Isomer
Catalogue No.:PA 03 3511004
(3S,11aR)-N-(2,4-Difluorobenzyl)-6-methoxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
Catalogue No.:PA 03 3511005
Molecular Formula : C20H19F2N3O5
Molecular Weight : 419.38
(3S,11aR)-N-(4-Fluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
Catalogue No.:PA 03 3511006
Molecular Formula : C19H18FN3O5
Molecular Weight : 387.37
(3S,11aR)-N-Benzyl-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
Catalogue No.:PA 03 3511007
Molecular Formula : C19H19N3O5
Molecular Weight : 369.38
(3S,11aR)-6-Methoxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxylic Acid; (3S,11aR)-2,3,5,7,11,11a-Hexahydro-6-methoxy-3-methyl-5,7-dioxooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxylic Acid;
Catalogue No.:PA 03 3511008
Molecular Formula : C13H14N2O6
Molecular Weight : 294.26
(3S,11aR)-N-(2-Fluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
Catalogue No.:PA 03 3511009
(3S,11aR)-N-(2,6-Difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
Catalogue No.:PA 03 3511010
Cabotegravir-D3
Catalogue No.:PA STI 089741
Molecular Formula : C19H14D3F2N3O5
Molecular Weight : 408.38
(S)-N-(2,4-Difluorobenzyl)-9-hydroxy-2-(1-hydroxypropan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide
Catalogue No.:PA 03 3511011
(3S,11aR)-6-Hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxylic acid
Catalogue No.:PA 03 3511012
Molecular Formula : C12H12N2O6
Molecular Weight : 280.24
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