Cabazitaxel Isopropanol and its Impurities

Cabazitaxel Isopropanol, sold under the brand name Jevtana, is a semi-synthetic derivative of a natural taxoid. Cabazitaxel in combination with prednisone is a treatment option for hormone-refractory prostate cancer following docetaxel-based treatment. Reference standards of Cabazitaxel Isopropanol API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.