Bosutinib-impurities | Pharmaffiliates

bosutinib and its Impurities

Bosutinib is used to treat chronic myeloid leukaemia that has an abnormal chromosome called the Philadelphia chromosome. It is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity.. Reference standards of Bosutinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 55 results for bosutinib Impurities
PA 02 92540

4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(piperazin-1-yl)propoxy)quinoline-3-carbonitrile

4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(piperazin-1-yl)propoxy)quinoline-3-carbonitrile

  • Catalogue No.:PA 02 92540

  • CAS :

    380843-81-2

  • Molecular Formula : C25H27Cl2N5O3

  • Molecular Weight : 516.42

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PA 02 0921008

Bosutinib Dimer Impurity

Bosutinib Dimer Impurity

  • Catalogue No.:PA 02 0921008

  • CAS :

    NA

  • Molecular Formula : C47H46Cl4N8O6

  • Molecular Weight : 960.74

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PA 02 0921010

4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-propoxyquinoline-3-carbonitrile

4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-propoxyquinoline-3-carbonitrile

  • Catalogue No.:PA 02 0921010

  • CAS :

    2095306-25-3

  • Molecular Formula : C21H19Cl2N3O3

  • Molecular Weight : 432.3

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PA 02 0921012

Bosutinib Desmethyl Impurity

Bosutinib Desmethyl Impurity

  • Catalogue No.:PA 02 0921012

  • CAS :

    2468737-92-8

  • Molecular Formula : C25H27Cl2N5O3

  • Molecular Weight : 516.42

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PA 02 0921013

Bosutinib N-Oxide

Bosutinib N-Oxide

  • Catalogue No.:PA 02 0921013

  • CAS :

    2468737-96-2

  • Molecular Formula : C26H29Cl2N5O4

  • Molecular Weight : 546.45

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PA 02 0921027

Bosutinib Regio Isomer Impurity

Bosutinib Regio Isomer Impurity

  • Catalogue No.:PA 02 0921027

  • CAS :

    1391063-17-4

  • Molecular Formula : C26H29Cl2N5O3

  • Molecular Weight : 530.45

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PA 02 0921014

4-Chloro-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile

4-Chloro-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile

  • Catalogue No.:PA 02 0921014

  • CAS :

    492444-39-0

  • Molecular Formula : C19H23ClN4O2

  • Molecular Weight : 374.87

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PA 02 0921015

4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile

4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-hydroxy-6-methoxy-3-quinolinecarbonitrile

  • Catalogue No.:PA 02 0921015

  • CAS :

    1460227-29-5

  • Molecular Formula : C18H13Cl2N3O3

  • Molecular Weight : 390.22

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PA 02 0921016

4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6,7-dimethoxy-3-quinolinecarbonitrile

4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6,7-dimethoxy-3-quinolinecarbonitrile

  • Catalogue No.:PA 02 0921016

  • CAS :

    380843-12-9

  • Molecular Formula : C19H15Cl2N3O3

  • Molecular Weight : 404.25

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PA 02 0921017

N-Desmethylpiperazine Hydroxy Bosutinib

N-Desmethylpiperazine Hydroxy Bosutinib

  • Catalogue No.:PA 02 0921017

  • CAS :

    2724727-55-1

  • Molecular Formula : C21H19Cl2N3O4

  • Molecular Weight : 448.3

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PA 02 0921018

7-(3-Chloropropoxy)-4-(2,4-dichloro-5-methoxyanilino)-6-methoxyquinoline-3-carbonitrile

7-(3-Chloropropoxy)-4-(2,4-dichloro-5-methoxyanilino)-6-methoxyquinoline-3-carbonitrile

  • Catalogue No.:PA 02 0921018

  • CAS :

    380844-49-5

  • Molecular Formula : C21H18Cl3N3O3

  • Molecular Weight : 466.74

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PA 02 92000

Bosutinib - API Standards

Bosutinib

  • Catalogue No.:PA 02 92000

  • CAS :

    380843-75-4

  • Molecular Formula : C26H29Cl2N5O3

  • Molecular Weight : 530.45

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PA 02 92510

4-((3,5-Dichloro-4-methoxyphenyl)amino)-6-methoxy-7-(3-(1-methylpiperidin-4-yl)propoxy)quinoline-3-carbonitrile

4-((3,5-Dichloro-4-methoxyphenyl)amino)-6-methoxy-7-(3-(1-methylpiperidin-4-yl)propoxy)quinoline-3-carbonitrile

  • Catalogue No.:PA 02 92510

  • CAS :

    NA

  • Molecular Formula : C27H30Cl2N4O3

  • Molecular Weight : 529.46

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PA 02 92680

2-Cyano-N-(2,4-Dichloro-5-Methoxyphenyl)Acetamide

2-Cyano-N-(2,4-Dichloro-5-Methoxyphenyl)Acetamide

  • Catalogue No.:PA 02 92680

  • CAS :

    846023-24-3

  • Molecular Formula : C10H8Cl2N2O2

  • Molecular Weight : 259.09

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PA 02 0921000

Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate

Methyl 2-amino-4-(3-chloropropoxy)-5-methoxybenzoate

  • Catalogue No.:PA 02 0921000

  • CAS :

    214470-59-4

  • Molecular Formula : C12H16ClNO4

  • Molecular Weight : 273.71

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PA 02 0921001

2-(3-Bromopropoxy)-1-methoxy-4-nitrobenzene

2-(3-Bromopropoxy)-1-methoxy-4-nitrobenzene

  • Catalogue No.:PA 02 0921001

  • CAS :

    219786-51-3

  • Molecular Formula : C10H12BrNO4

  • Molecular Weight : 290.11

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PA 02 0921002

2-Cyano-N-(2,4-dichlorophenyl)acetamide

2-Cyano-N-(2,4-dichlorophenyl)acetamide

  • Catalogue No.:PA 02 0921002

  • CAS :

    17722-32-6

  • Molecular Formula : C9H6Cl2N2O

  • Molecular Weight : 229.06

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PA 02 0921003

2-Cyano-N-(3,5-dichloro-4-methoxyphenyl)-acetamide

2-Cyano-N-(3,5-dichloro-4-methoxyphenyl)-acetamide

  • Catalogue No.:PA 02 0921003

  • CAS :

    1821033-10-6

  • Molecular Formula : C10H8Cl2N2O2

  • Molecular Weight : 259.09

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PA 02 0921004

N-(2,4-Dichloro-5-methoxyphenyl)acetamide

N-(2,4-Dichloro-5-methoxyphenyl)acetamide

  • Catalogue No.:PA 02 0921004

  • CAS :

    65182-98-1

  • Molecular Formula : C9H9Cl2NO2

  • Molecular Weight : 234.08

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PA 02 0921005

N-(4-chloro-3-methoxyphenyl)-2-cyanoacetamide

N-(4-chloro-3-methoxyphenyl)-2-cyanoacetamide

  • Catalogue No.:PA 02 0921005

  • CAS :

    879644-03-8

  • Molecular Formula : C10H9ClN2O2

  • Molecular Weight : 224.64

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PA 02 0921006

4-((2,4-Dichloro-5-hydroxyphenyl)amino)-6-hydroxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile

4-((2,4-Dichloro-5-hydroxyphenyl)amino)-6-hydroxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile

  • Catalogue No.:PA 02 0921006

  • CAS :

    2468737-94-0

  • Molecular Formula : C24H25Cl2N5O3

  • Molecular Weight : 502.4

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PA 02 0921007

N-(2-Chloro-5-methoxyphenyl)-2-cyanoacetamide

N-(2-Chloro-5-methoxyphenyl)-2-cyanoacetamide

  • Catalogue No.:PA 02 0921007

  • CAS :

    1307530-78-4

  • Molecular Formula : C10H9ClN2O2

  • Molecular Weight : 224.64

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PA 02 0921009

2-Cyano-N-(2,4-dichloro-5-methoxy phenyl)-3-{4-methoxy-3-[3-(4-methyl piperazin-1-yl)-propoxy]- phenylamino} acrylamide

2-Cyano-N-(2,4-dichloro-5-methoxy phenyl)-3-{4-methoxy-3-[3-(4-methyl piperazin-1-yl)-propoxy]- phenylamino} acrylamide

  • Catalogue No.:PA 02 0921009

  • CAS :

    846023-56-1

  • Molecular Formula : C26H31Cl2N5O4

  • Molecular Weight : 548.47

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PA 02 0921011

7,7'-((Piperazine-1,4-diylbis(propane-3,1-diyl))bis(oxy))bis(4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile)

7,7'-((Piperazine-1,4-diylbis(propane-3,1-diyl))bis(oxy))bis(4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile)

  • Catalogue No.:PA 02 0921011

  • CAS :

    2095306-26-4

  • Molecular Formula : C46H44Cl4N8O6

  • Molecular Weight : 946.71

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PA 02 0921019

Methyl 4-(3-chloropropoxy)-3-methoxybenzoate

Methyl 4-(3-chloropropoxy)-3-methoxybenzoate

  • Catalogue No.:PA 02 0921019

  • CAS :

    111627-40-8

  • Molecular Formula : C12H15ClO4

  • Molecular Weight : 258.7

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PA 02 0921022

2-Bromo-4-(3-chloropropoxy)-5-methoxybenzoic Acid

2-Bromo-4-(3-chloropropoxy)-5-methoxybenzoic Acid

  • Catalogue No.:PA 02 0921022

  • CAS :

    1910109-73-7

  • Molecular Formula : C11H12BrClO4

  • Molecular Weight : 323.57

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PA 02 0921023

Ethyl (Z)-3-(2-bromo-4-(3-chloropropoxy)-5-methoxyphenyl)-2-cyano-3-hydroxyacrylate

Ethyl (Z)-3-(2-bromo-4-(3-chloropropoxy)-5-methoxyphenyl)-2-cyano-3-hydroxyacrylate

  • Catalogue No.:PA 02 0921023

  • CAS :

    1910109-74-8

  • Molecular Formula : C16H17BrClNO5

  • Molecular Weight : 418.67

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PA 02 0921024

(E)-3-(2-Bromo-4-(3-chloropropoxy)-5-methoxyphenyl)-3-hydroxyacrylonitrile

(E)-3-(2-Bromo-4-(3-chloropropoxy)-5-methoxyphenyl)-3-hydroxyacrylonitrile

  • Catalogue No.:PA 02 0921024

  • CAS :

    NA

  • Molecular Formula : C13H13BrClNO3

  • Molecular Weight : 346.61

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PA 02 0921025

(E)-3-Amino-2-(2-bromo-4-(3-chloropropoxy)-5-methoxybenzoyl)acrylonitrile

(E)-3-Amino-2-(2-bromo-4-(3-chloropropoxy)-5-methoxybenzoyl)acrylonitrile

  • Catalogue No.:PA 02 0921025

  • CAS :

    1910109-76-0

  • Molecular Formula : C14H14BrClN2O3

  • Molecular Weight : 373.63

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PA 02 0921026

7-(3-Chloropropoxy)-4-hydroxy-6-methoxyquinoline-3-carbonitrile

7-(3-Chloropropoxy)-4-hydroxy-6-methoxyquinoline-3-carbonitrile

  • Catalogue No.:PA 02 0921026

  • CAS :

    214470-66-3

  • Molecular Formula : C14H13ClN2O3

  • Molecular Weight : 292.72

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PA 02 0921021

Methyl 4-(3-chloropropoxy)-5-methoxy-2-nitrobenzoate

Methyl 4-(3-chloropropoxy)-5-methoxy-2-nitrobenzoate

  • Catalogue No.:PA 02 0921021

  • CAS :

    214470-57-2

  • Molecular Formula : C12H14ClNO6

  • Molecular Weight : 303.7

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PA 02 0921020

Methyl (E)-4-(3-chloropropoxy)-2-((2-cyanovinyl)amino)-5-methoxybenzoate

Methyl (E)-4-(3-chloropropoxy)-2-((2-cyanovinyl)amino)-5-methoxybenzoate

  • Catalogue No.:PA 02 0921020

  • CAS :

    1248588-02-4

  • Molecular Formula : C15H17ClN2O4

  • Molecular Weight : 324.76

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PA 02 0921028

 7,7'-(Propane-1,3-diylbis(oxy))bis(4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile)

7,7'-(Propane-1,3-diylbis(oxy))bis(4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile)

  • Catalogue No.:PA 02 0921028

  • CAS :

    2095306-27-5

  • Molecular Formula : C39H30Cl4N6O6

  • Molecular Weight : 820.51

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PA 02 0921029

1,3-bis(2-Methoxy-5-nitrophenoxy)propane

1,3-bis(2-Methoxy-5-nitrophenoxy)propane

  • Catalogue No.:PA 02 0921029

  • CAS :

    2095306-22-0

  • Molecular Formula : C17H18N2O8

  • Molecular Weight : 378.34

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PA 02 0921030

4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-nitrosopiperazin-1-yl)propoxy)quinoline-3-carbonitrile

4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-nitrosopiperazin-1-yl)propoxy)quinoline-3-carbonitrile

  • Catalogue No.:PA 02 0921030

  • CAS :

    NA

  • Molecular Formula : C25H26Cl2N6O4

  • Molecular Weight : 545.42

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PA 02 0921031

Bosutinib Oxydechlorinated Impurity

Bosutinib Oxydechlorinated Impurity

  • Catalogue No.:PA 02 0921031

  • CAS :

    NA

  • Molecular Formula : C26H30ClN5O4

  • Molecular Weight : 512.01

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PAI 02 092001

7-(3-Chloropropoxy)-4-((2,4-dichloro-5-hydroxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile

7-(3-Chloropropoxy)-4-((2,4-dichloro-5-hydroxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile

  • Catalogue No.:PAI 02 092001

  • CAS :

    NA

  • Molecular Formula : C20H16Cl3N3O3

  • Molecular Weight : 452.72

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PAI 02 092002

tert-Butyl 4-(3-((3-cyano-4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinolin-7-yl)oxy)propyl)piperazine-1-carboxylate

tert-Butyl 4-(3-((3-cyano-4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinolin-7-yl)oxy)propyl)piperazine-1-carboxylate

  • Catalogue No.:PAI 02 092002

  • CAS :

    1613270-82-8

  • Molecular Formula : C30H35Cl2N5O5

  • Molecular Weight : 616.54

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PA STI 089532

Bosutinib D8

Bosutinib D8

  • Catalogue No.:PA STI 089532

  • CAS :

    2733145-45-2

  • Molecular Formula : C26H21D8Cl2N5O3

  • Molecular Weight : 538.5

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PAI 02 092003

2,4-Dichloro-N-(4-chlorobutyl)-5-methoxyaniline

2,4-Dichloro-N-(4-chlorobutyl)-5-methoxyaniline

  • Catalogue No.:PAI 02 092003

  • CAS :

    NA

  • Molecular Formula : C11H14Cl3NO

  • Molecular Weight : 282.59

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PAI 02 092004

4-((3-Bromopropyl)(2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile

4-((3-Bromopropyl)(2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile

  • Catalogue No.:PAI 02 092004

  • CAS :

    NA

  • Molecular Formula : C29H34BrCl2N5O3

  • Molecular Weight : 651.43

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PAI 02 092005

5-Chloro-7-(3-hydroxypropoxy)-6-methoxyquinoline-3-carbonitrile

5-Chloro-7-(3-hydroxypropoxy)-6-methoxyquinoline-3-carbonitrile

  • Catalogue No.:PAI 02 092005

  • CAS :

    NA

  • Molecular Formula : C14H13ClN2O3

  • Molecular Weight : 292.72

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PAI 02 092006

4-Chloro-6,7-dimethoxyquinoline-3-carbonitrile

4-Chloro-6,7-dimethoxyquinoline-3-carbonitrile

  • Catalogue No.:PAI 02 092006

  • CAS :

    214470-55-0

  • Molecular Formula : C12H9ClN2O2

  • Molecular Weight : 248.67

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PAI 02 092007

4-Chloro-6-methoxy-7-propoxyquinoline-3-carbonitrile

4-Chloro-6-methoxy-7-propoxyquinoline-3-carbonitrile

  • Catalogue No.:PAI 02 092007

  • CAS :

    NA

  • Molecular Formula : C14H13ClN2O2

  • Molecular Weight : 276.72

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PAI 02 092008

4-Chloro-7-(3-hydroxypropoxy)-6-methoxyquinoline-3-carbonitrile

4-Chloro-7-(3-hydroxypropoxy)-6-methoxyquinoline-3-carbonitrile

  • Catalogue No.:PAI 02 092008

  • CAS :

    2760140-40-5

  • Molecular Formula : C14H13ClN2O3

  • Molecular Weight : 292.72

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PAI 02 092009

7,7'-(Propane-1,3-diylbis(oxy))bis(4-chloro-6-methoxyquinoline-3-carbonitrile)

7,7'-(Propane-1,3-diylbis(oxy))bis(4-chloro-6-methoxyquinoline-3-carbonitrile)

  • Catalogue No.:PAI 02 092009

  • CAS :

    NA

  • Molecular Formula : C25H18Cl2N4O4

  • Molecular Weight : 509.34

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PAI 02 092010

4-((2,4-Dichloro-5-methoxyphenyl)amino)-7-(3-((2,4-dichloro-5-methoxyphenyl)amino)propoxy)-6-methoxyquinoline-3-carbonitrile

4-((2,4-Dichloro-5-methoxyphenyl)amino)-7-(3-((2,4-dichloro-5-methoxyphenyl)amino)propoxy)-6-methoxyquinoline-3-carbonitrile

  • Catalogue No.:PAI 02 092010

  • CAS :

    NA

  • Molecular Formula : C28H24Cl4N4O4

  • Molecular Weight : 622.32

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PAI 02 092011

4-Chloro-7-(3-chloropropoxy)-6-methoxyquinoline-3-carbonitrile

4-Chloro-7-(3-chloropropoxy)-6-methoxyquinoline-3-carbonitrile

  • Catalogue No.:PAI 02 092011

  • CAS :

    214470-68-5

  • Molecular Formula : C14H12Cl2N2O2

  • Molecular Weight : 311.16

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PA 02 0921032

Bosutinib 4-piperazine

Bosutinib 4-piperazine

  • Catalogue No.:PA 02 0921032

  • CAS :

    NA

  • Molecular Formula : C19H23ClN4O3

  • Molecular Weight : 390.87

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PA 02 0921033

1-(3-(2-Methoxy-5-nitrophenoxy)propyl)-4-nitrosopiperazine

1-(3-(2-Methoxy-5-nitrophenoxy)propyl)-4-nitrosopiperazine

  • Catalogue No.:PA 02 0921033

  • CAS :

    NA

  • Molecular Formula : C14H20N4O5

  • Molecular Weight : 324.34

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PA 02 0921034

2-Cyano-N-(2,4-dichloro-5-methoxyphenyl)-3-((4-methoxy-3-(3-(4-nitrosopiperazin-1-yl)propoxy)phenyl)amino)acrylamide

2-Cyano-N-(2,4-dichloro-5-methoxyphenyl)-3-((4-methoxy-3-(3-(4-nitrosopiperazin-1-yl)propoxy)phenyl)amino)acrylamide

  • Catalogue No.:PA 02 0921034

  • CAS :

    NA

  • Molecular Formula : C25H28Cl2N6O5

  • Molecular Weight : 563.44

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PA 02 0921035

N-(3-Cyano-6-methoxy-7-propoxyquinolin-4-yl)-N-(2,4-dichloro-5-methoxyphenyl)nitrous amide

N-(3-Cyano-6-methoxy-7-propoxyquinolin-4-yl)-N-(2,4-dichloro-5-methoxyphenyl)nitrous amide

  • Catalogue No.:PA 02 0921035

  • CAS :

    NA

  • Molecular Formula : C21H18Cl2N4O4

  • Molecular Weight : 461.3

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PA 02 0921036

N,N'-((Propane-1,3-diylbis(oxy))bis(3-cyano-6-methoxyquinoline-7,4-diyl))bis(N-(2,4-dichloro-5-methoxyphenyl)nitrous amide)

N,N'-((Propane-1,3-diylbis(oxy))bis(3-cyano-6-methoxyquinoline-7,4-diyl))bis(N-(2,4-dichloro-5-methoxyphenyl)nitrous amide)

  • Catalogue No.:PA 02 0921036

  • CAS :

    NA

  • Molecular Formula : C39H28Cl4N8O8

  • Molecular Weight : 878.5

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PA 02 0921037

N,N'-(((Piperazine-1,4-diylbis(propane-3,1-diyl))bis(oxy))bis(3-cyano-6-methoxyquinoline-7,4-diyl))bis(N-(2,4-dichloro-5-methoxyphenyl)nitrous amide)

N,N'-(((Piperazine-1,4-diylbis(propane-3,1-diyl))bis(oxy))bis(3-cyano-6-methoxyquinoline-7,4-diyl))bis(N-(2,4-dichloro-5-methoxyphenyl)nitrous amide)

  • Catalogue No.:PA 02 0921037

  • CAS :

    NA

  • Molecular Formula : C46H42Cl4N10O8

  • Molecular Weight : 1004.7

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PA 02 0921038

N-(3-Cyano-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yl)-N-(2,4-dichloro-5-methoxyphenyl)nitrous amide

N-(3-Cyano-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yl)-N-(2,4-dichloro-5-methoxyphenyl)nitrous amide

  • Catalogue No.:PA 02 0921038

  • CAS :

    NA

  • Molecular Formula : C26H28Cl2N6O4

  • Molecular Weight : 559.45

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