Bosentan is used to treat people with moderate pulmonary arterial hypertension and to reduce the number of digital ulcers. It is available as film-coated tablets or as dispersable tablets for oral suspension.. Reference standards of Bosentan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Bosentan
Catalogue No.:PA 29 13000
CAS :
Molecular Formula : C27H29N5O6S
Molecular Weight : 551.61
Bosentan-d4
Catalogue No.:PA STI 014260
Molecular Formula : C27H25D4N5O6S
Molecular Weight : 555.64
Bosentan-13C2, d4
Catalogue No.:PA STI 014270
Molecular Formula : C2513C2H25D4N5O6S
Molecular Weight : 557.62
Desmethyl Bosentan-d4
Catalogue No.:PA STI 028100
Molecular Formula : C26H23D4N5O6S
Molecular Weight : 541.61
Hydroxy Bosentan-d4
Catalogue No.:PA STI 047970
Molecular Formula : C27H25D4N5O7S
Molecular Weight : 571.64
Hydroxy Bosentan-d6
Catalogue No.:PA STI 047980
Molecular Formula : C27H23D6N5O7S
Molecular Weight : 573.65
Hydroxy Desmethyl Bosentan-d4
Catalogue No.:PA STI 048560
Molecular Formula : C26H23D4N5O7S
Molecular Weight : 557.61
Bosentan Related Compound C (1,2-bis({6-[4-(tert-butyl)phenylsulfonamido]-5-(2-methoxyphenoxy)-[2,2 (1076148)
Catalogue No.:PA USP1076148
Molecular Formula : NA
Molecular Weight : NA
Bosentan Related Compound A (4-(tert-butyl)-N-[6-chloro-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-y (1076126)
Catalogue No.:PA USP1076126
Bosentan Related Compound D (4,6-dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine) (1076159)
Catalogue No.:PA USP1076159
Bosentan (1076115)
Catalogue No.:PA USP1076115
Bosentan Related Compound B (4-(tert-butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4- (1076137)
Catalogue No.:PA USP1076137
Bosentan Related Compound E (4-(tert-butyl)benzenesulfonamide) (1076160)
Catalogue No.:PA USP1076160
Bosentan-13C6
Catalogue No.:PA STI 014271
Molecular Formula : C2113C6H29N5O6S
Molecular Weight : 557.57
Bosentan Sodium
Catalogue No.:PA 29 0131000
Molecular Formula : C27H28N5NaO6S
Molecular Weight : 573.60
Bosentan Potassium
Catalogue No.:PA 29 0131001
Molecular Formula : C27H28KN5O6S
Molecular Weight : 589.71
Bosentan sulfide
Catalogue No.:PA 29 0131002
Molecular Formula : C27H29N5O4S
Molecular Weight : 519.62
Bosentan sulfoxide
Catalogue No.:PA 29 0131003
Molecular Formula : C27H29N5O5S
Molecular Weight : 535.62
4-(Tert-butyl)-N-(5-hydroxy-6-(2-(2-hydroxyethoxy)ethoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide
Catalogue No.:PA 29 0131004
Molecular Formula : C22H27N5O6S
Molecular Weight : 489.55
Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl]-
Catalogue No.:PA 29 0131005
Molecular Formula : C20H21N5O4S
Molecular Weight : 427.48
6-Amino-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-ol
Catalogue No.:PA 29 0131006
Molecular Formula : C15H13N5O3
Molecular Weight : 311.3
2-((6-Amino-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethan-1-ol
Catalogue No.:PA 29 0131007
Molecular Formula : C17H17N5O4
Molecular Weight : 355.35
Isopropyl 4-(tert-butyl)benzenesulfonate
Catalogue No.:PA 29 0131008
Molecular Formula : C13H20O3S
Molecular Weight : 256.36
2-Hydroxyethyl 4-(tert-butyl)benzenesulfonate
Catalogue No.:PA 29 0131009
Molecular Formula : C12H18O4S
Molecular Weight : 258.33
4-(tert-Butyl)benzenesulfonohydrazide
Catalogue No.:PAI 29 013001
Molecular Formula : C10H16N2O2S
Molecular Weight : 228.31
2-((6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)oxy)ethan-1-ol
Catalogue No.:PA 29 0131010
Molecular Formula : C17H15ClN4O4
Molecular Weight : 374.78
Diethyl 2-(benzyloxy)malonate
Catalogue No.:PAI 29 013002
Molecular Formula : C14H18O5
Molecular Weight : 266.29
2-((Tetrahydro-2H-pyran-2-yl)oxy)ethan-1-ol
Catalogue No.:PAI 29 013003
Molecular Formula : C7H14O3
Molecular Weight : 146.19
2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethan-1-ol
Catalogue No.:PAI 29 013004
Molecular Formula : C9H18O4
Molecular Weight : 190.24
2-(tert-Butyl)benzenesulfonyl Chloride
Catalogue No.:PAI 29 013005
Molecular Formula : C10H13ClO2S
Molecular Weight : 232.72
6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-amine
Catalogue No.:PAI 29 013006
Molecular Formula : C15H12ClN5O2
Molecular Weight : 329.74
1,2-Bis(4-(tert-butyl)phenyl)disulfane
Catalogue No.:PAI 29 013007
Molecular Formula : C20H26S2
Molecular Weight : 330.55
bis(6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)amine
Catalogue No.:PAI 29 013008
Molecular Formula : C30H21Cl2N9O4
Molecular Weight : 642.46
4-Isopropylbenzenesulfonamide
Catalogue No.:PAI 29 013009
Molecular Formula : C9H13NO2S
Molecular Weight : 199.27
N-(6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-isopropylbenzenesulfonamide
Catalogue No.:PAI 29 013010
Molecular Formula : C24H22ClN5O4S
Molecular Weight : 511.98
4-(tert-Butyl)benzenesulfinic Chloride
Catalogue No.:PAI 29 013011
Molecular Formula : C10H13ClOS
Molecular Weight : 216.72
4-Chloro-5-(2-methoxyphenoxy)-6-(vinyloxy)-2,2'-bipyrimidine
Catalogue No.:PAI 29 013012
Molecular Formula : C17H13ClN4O3
Molecular Weight : 356.77
6-Hydroxy-5-methoxy-[2,2'-bipyrimidin]-4(3H)-one
Catalogue No.:PAI 29 013013
Molecular Formula : C9H8N4O3
Molecular Weight : 220.19
Diethyl 2-methoxymalonate
Catalogue No.:PAI 29 013014
Molecular Formula : C8H14O5
Molecular Weight : 190.2
4,6-Dichloro-5-methoxy-1,6-dihydro-2,2'-bipyrimidine
Catalogue No.:PAI 29 013015
Molecular Formula : C9H8Cl2N4O
Molecular Weight : 259.09
2-Propoxyethyl 4-methylbenzenesulfonate
Catalogue No.:PA 29 0131012
3-Ethoxypropyl 4-methylbenzenesulfonate
Catalogue No.:PA 29 0131011
Ethyl 2-(4-(chlorosulfonyl)phenyl)-2-methylpropanoate
Catalogue No.:PAI 29 013016
Molecular Formula : C12H15ClO4S
Molecular Weight : 290.76
4-(2-Methyl-1-((tetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)benzenesulfonamide
Catalogue No.:PAI 29 013017
Molecular Formula : C15H23NO4S
Molecular Weight : 313.41
N-(6-Chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-(2-methyl-1-((tetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)benzenesulfonamide
Catalogue No.:PAI 29 013018
Molecular Formula : C30H32ClN5O6S
Molecular Weight : 626.13
N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)-4-(2-methyl-1-((tetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)benzenesulfonamide
Catalogue No.:PAI 29 013019
Molecular Formula : C32H37N5O8S
Molecular Weight : 651.74
Ethyl 2-(4-(N-(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)sulfamoyl)phenyl)-2-methylpropanoate
Catalogue No.:PAI 29 013020
Molecular Formula : C27H26ClN5O6S
Molecular Weight : 584.04
Ethyl 2-(4-(N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)sulfamoyl)phenyl)-2-methylpropanoate
Catalogue No.:PAI 29 013021
Molecular Formula : C29H31N5O8S
Molecular Weight : 609.65
2-(4-(N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)sulfamoyl)phenyl)-2-methylpropanoic Acid
Catalogue No.:PAI 29 013022
Molecular Formula : C27H27N5O8S
Molecular Weight : 581.6
6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4(3H)-one
Catalogue No.:PA 29 0131013
Molecular Formula : C17H16N4O5
Molecular Weight : 356.34
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