Bilastine is used to relieve the symptoms of hayfever and other forms of allergic rhinitis. It is sold under the brand name Bilaxten. Reference standards of Bilastine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole Hydrochloride Sesquihydrate
Catalogue No.:PA 29 50540
CAS :
Molecular Formula : C16H24ClN3O . 1.5(H2O)
Molecular Weight : 318.85
Methyl 2-(4-(2-chloroacetyl)phenyl)-2-methylpropanoate
Catalogue No.:PA 29 50560
Molecular Formula : C13H15ClO3
Molecular Weight : 254.71
2-(3-(2-(4-(1-(2-Ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-2-methylpropanoic Acid
Catalogue No.:PA 29 50580
Molecular Formula : C28H37N3O3
Molecular Weight : 463.62
1’-Hydroxy Bilastine
Catalogue No.:PA 29 50510
Molecular Formula : C28H37N3O4
Molecular Weight : 479.62
Bilastine N-Oxide
Catalogue No.:PA 29 50520
Methyl 2-(4-(2-(4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-2-methylpropanoate
Catalogue No.:PA 29 0501000
Molecular Formula : C29H39N3O3
Molecular Weight : 477.65
Bilastine
Catalogue No.:PA 29 50000
2-(4-(2-(4-(1-(2-Methoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-2-methylpropanoic Acid
Catalogue No.:PA 29 0501006
Molecular Formula : C27H35N3O3
Molecular Weight : 449.6
2-(2-(4-(2-(4-(1-(2-Ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)propan-2-yl)-4,4-dimethyl-4,5-dihydrooxazole
Catalogue No.:PA 29 0501007
Molecular Formula : C32H44N4O2
Molecular Weight : 516.73
(1s,4r)-1-(4-(2-Carboxypropan-2-yl)phenethyl)-4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidine 1-oxide
Catalogue No.:PA 29 0501010
Bilastine Amide Impurity
Catalogue No.:PA 29 0501013
Molecular Formula : C32H46N4O3
Molecular Weight : 534.75
Bilastine Hydroxy Impurity
Catalogue No.:PA 29 0501014
Molecular Formula : C26H33N3O3
Molecular Weight : 435.57
2-(4-(2-(4-(1H-Benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-2-methylpropanoic Acid
Catalogue No.:PA 29 0501016
Molecular Formula : C24H29N3O2
Molecular Weight : 391.52
2-Amino-2-methylpropyl 2-(4-(2-(4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-2-methylpropanoate
Catalogue No.:PA 29 0501035
Bilastine-D6
Catalogue No.:PA STI 012800
Molecular Formula : C28H31D6N3O3
Molecular Weight : 469.65
2-(Piperidin-4-yl)-1H-benzo[d]imidazole Hydrate
Catalogue No.:PA 29 50530
Molecular Formula : C12H17N3O
Molecular Weight : 219.29
2-(4-(2-Chloroacetyl)phenyl)-N,N,2-trimethylpropanamide
Catalogue No.:PA 29 50550
Molecular Formula : C14H18ClNO2
Molecular Weight : 267.75
Methyl 2-(4-(2-chloroethyl)phenyl)-2-methylpropanoate
Catalogue No.:PA 29 50570
Molecular Formula : C13H17ClO2
Molecular Weight : 240.73
2-(1-(2-Ethoxyethyl)piperidin-4-yl)-1H-benzo[d]imidazole
Catalogue No.:PA 29 0501001
Molecular Formula : C16H23N3O
Molecular Weight : 273.38
1-(2-Ethoxyethyl)-2-(1-(2-ethoxyethyl)piperidin-4-yl)-1H-benzo[d]imidazole
Catalogue No.:PA 29 0501002
Molecular Formula : C20H31N3O2
Molecular Weight : 345.49
1-(2-Ethoxy-ethyl)-2-piperidin-4-yl-1H-benzimidazole
Catalogue No.:PA 29 0501003
4-(2-Chloroethyl)-N-methoxy-N,α,α-trimethyl-benzeneacetamide
Catalogue No.:PA 29 0501004
Molecular Formula : C14H20ClNO2
Molecular Weight : 269.77
2-(4-(2-(4-(1-(2-Ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-N-methoxy-N,2-dimethylpropanamide
Catalogue No.:PA 29 0501005
Molecular Formula : C30H42N4O3
Molecular Weight : 506.69
N-Boc 1-(2-Ethyoxyethyl)-2-(4-piperidinyl)-1H-benzimidazole
Catalogue No.:PA 29 0501008
Molecular Formula : C21H31N3O3
Molecular Weight : 373.5
(1r,4s)-1-(4-(2-Carboxypropan-2-yl)phenethyl)-4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidine 1-oxide
Catalogue No.:PA 29 0501009
Methyl 2-(3-(2-chloroethyl)phenyl)-2-methylpropanoate
Catalogue No.:PA 29 0501011
2-(1-Nitrosopiperidin-4-yl)-1H-benzo[d]imidazole
Catalogue No.:PA 29 0501012
Molecular Formula : C12H14N4O
Molecular Weight : 230.27
1-(2-Ethoxyethyl)-2-(1-nitrosopiperidin-4-yl)-1H-benzo[d]imidazole
Catalogue No.:PA 29 0501015
Molecular Formula : C16H22N4O2
Molecular Weight : 302.38
1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride
Catalogue No.:PA 29 0501017
Molecular Formula : C16H24ClN3O
Molecular Weight : 309.84
2-(2-(1-(4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl)piperidin-4-yl)-1H-benzo[d]imidazol-1-yl)ethan-1-ol
Catalogue No.:PA 29 0501018
Molecular Formula : C30H40N4O2
Molecular Weight : 488.68
2-Desetoxyethyl-4,5-Dihydrooxazole Bilastine
Catalogue No.:PA 29 0501019
Molecular Formula : C28H36N4O
Molecular Weight : 444.62
2-(4-(2-(4-(1-(4-(2-Carboxypropan-2-yl)phenethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-2-methylpropanoic Acid
Catalogue No.:PA 29 0501020
Molecular Formula : C36H43N3O4
Molecular Weight : 581.76
2-Piperidin-4-yl-1H-benzimidazole
Catalogue No.:PA 29 0501021
Molecular Formula : C12H15N3
Molecular Weight : 201.27
Methyl 2-(4-(2-(4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)acetyl)phenyl)-2-methylpropanoate
Catalogue No.:PAI 29 050001
Molecular Formula : C29H37N3O4
Molecular Weight : 491.63
Methyl 2-(4-(2-(4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)-1-hydroxyethyl)phenyl)-2-methylpropanoate
Catalogue No.:PAI 29 050002
Molecular Formula : C29H39N3O4
Molecular Weight : 493.65
Methyl 2-methyl-2-(4-(2-(tosyloxy)ethyl)phenyl)propanoate
Catalogue No.:PA 29 0501022
Molecular Formula : C20H24O5S
Molecular Weight : 376.47
1-Nitroso-2-(1-nitrosopiperidin-4-yl)-1H-benzo[d]imidazole
Catalogue No.:PA 29 0501023
Molecular Formula : C12H13N5O2
Molecular Weight : 259.27
2-(4-(2-Chloroacetyl)phenyl)-N-methoxy-N,2-dimethylpropanamide
Catalogue No.:PA 29 0501024
Molecular Formula : C14H18ClNO3
Molecular Weight : 283.75
2-(4-(2-Bromoethyl)phenyl)-2-methylpropanoic Acid
Catalogue No.:PA 29 0501025
Molecular Formula : C12H15BrO2
Molecular Weight : 271.15
2-(3-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenyl)ethan-1-ol
Catalogue No.:PA 29 0501026
Molecular Formula : C16H23NO2
Molecular Weight : 261.37
4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate
Catalogue No.:PA 29 0501027
Molecular Formula : C23H29NO4S
Molecular Weight : 415.55
Bilastine-d4
Catalogue No.:PA STI 089515
Molecular Formula : C28H33D4N3O3
Molecular Weight : 467.65
(4-(1H-Benzo[d]imidazol-2-yl)piperidin-1-yl)(piperidin-4-yl)methanone
Catalogue No.:PA 29 0501028
Molecular Formula : C18H24N4O
Molecular Weight : 312.42
2-Methoxyethyl 4-methylbenzenesulfonate
Catalogue No.:PA 29 0501029
Molecular Formula : C10H14O4S
Molecular Weight : 230.28
2-Methyl-2-(4-(2-(tosyloxy)ethyl)phenyl)propanoic Acid
Catalogue No.:PA 29 0501030
Molecular Formula : C19H22O5S
Molecular Weight : 362.44
N,N-Diethyl-4-methylbenzenesulfonamide
Catalogue No.:PA 29 0501031
Molecular Formula : C11H17NO2S
Molecular Weight : 227.32
2-(2-(4-Bromophenyl)propan-2-yl)-4,4-dimethyl-4,5-dihydrooxazole
Catalogue No.:PA 29 0501032
Molecular Formula : C14H18BrNO
Molecular Weight : 296.21
2-Methyl-2-(4-vinylphenyl)propanoic Acid
Catalogue No.:PA 29 0501033
Molecular Formula : C12H14O2
Molecular Weight : 190.24
2-(4-(2-(4-(1H-Benzo[d]imidazol-2-yl)piperidin-1-yl)acetyl)phenyl)-2-methylpropanoic Acid
Catalogue No.:PA 29 0501034
Molecular Formula : C24H27N3O3
Molecular Weight : 405.5
2-(2-(2-(4-(1-(2-Ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)acetyl)phenyl)-2-methylpropanoic Acid
Catalogue No.:PAI 29 050003
Molecular Formula : C28H35N3O4
Molecular Weight : 477.61
2-(2-(2-(4-(1-(2-Ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)-1-hydroxyethyl)phenyl)-2-methylpropanoic Acid
Catalogue No.:PAI 29 050004
Bilastine Impurity D (IMPB052)
Catalogue No.:PA IMPB052
Molecular Formula : NA
Molecular Weight : NA
Bilastine Impurity E (IMPB053)
Catalogue No.:PA IMPB053
Bilastine (IPRSB049)
Catalogue No.:PA IPRSB049
Bilastine Impurity B (IMPB054)
Catalogue No.:PA IMPB054
2-(2-(4-(2-Chloroethyl)phenyl)propan-2-yl)-4,4-dimethyl-4,5-dihydrooxazole
Catalogue No.:PA 29 0501036
Molecular Formula : C16H22ClNO
Molecular Weight : 279.81
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