bendamustine and its Impurities
A drug that belongs to the family of alkylating agents, It is a nitrogen mustard which is used for the treatment of chronic lymphocytic leukemia and lymphomas. As an alkylating agent it causes intra-strand and inter-strand cross-links between DNA bases. Reference standards of Bendamustine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


4-(5-((2-((4-(5-((2-Chloroethyl)(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid
4-(5-((2-((4-(5-((2-Chloroethyl)(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoyl)oxy)ethyl)(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid
Catalogue No.:PA 02 07760
CAS :
1219709-87-1
Molecular Formula : C32H43ClN6O6
Molecular Weight : 643.17

![5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl- PA 02 0681002](https://www.pharmaffiliates.com/pimages/PA020681002.jpg)
5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
Catalogue No.:PA 02 0681002
CAS :
898224-95-8
Molecular Formula : C18H26ClN3O3
Molecular Weight : 367.87


2-Hydroxypropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
2-Hydroxypropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
Catalogue No.:PA 02 0681007
CAS :
1219709-88-2
Molecular Formula : C19H27Cl2N3O3
Molecular Weight : 416.34


1-Hydroxypropan-2-yl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
1-Hydroxypropan-2-yl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
Catalogue No.:PA 02 0681008
CAS :
1219709-89-3
Molecular Formula : C19H27Cl2N3O3
Molecular Weight : 416.34