Belzutifan, sold under the brand name Welireg, is a medication used for the treatment of von Hippel–Lindau disease-associated renal cell carcinoma. Reference standards of Belzutifan API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Belzutifan
Catalogue No.:PA 02 2420000
CAS :
Molecular Formula : C17H12F3NO4S
Molecular Weight : 383.34
3-(((1S,2S,3S)-2,3-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile
Catalogue No.:PA 02 2421000
rel-3-(((1R,2R,3S)-2,3-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile
Catalogue No.:PA 02 2421001
3-(((1R,2S,3R)-2,3-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile
Catalogue No.:PA 02 2421002
3-Fluoro-5-(((1S,2R,3R)-2-fluoro-1,3-dihydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)benzonitrile
Catalogue No.:PA 02 2421003
Molecular Formula : C17H13F2NO5S
Molecular Weight : 381.35
3-(((1S,2S,3R)-3-(((1S,2R,3R)-4-(3-Cyano-5-fluorophenoxy)-2-fluoro-3-(2-methoxyethoxy)-7-(methylsulfonyl)-2,3-dihydro-1H-inden-1-yl)oxy)-2-fluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile
Catalogue No.:PA 02 2421004
Molecular Formula : C37H30F4N2O10S2
Molecular Weight : 802.76
3-(((1S,2S,3S)-1-(((1R,2S,3S)-7-(3-Cyano-5-fluorophenoxy)-2-fluoro-3-hydroxy-4-(methylsulfonyl)-2,3-dihydro-1H-inden-1-yl)oxy)-2-fluoro-3-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile
Catalogue No.:PA 02 2421005
Molecular Formula : C34H24F4N2O9S2
Molecular Weight : 744.68
3-(((1S,2S,3R)-3-(((1S,2S,3R)-4-(3-Cyano-5-fluorophenoxy)-2,3-difluoro-7-(methylsulfonyl)-2,3-dihydro-1H-inden-1-yl)oxy)-2-fluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile
Catalogue No.:PA 02 2421006
Molecular Formula : C34H23F5N2O8S2
Molecular Weight : 746.68
3-Fluoro-5-(((1R,2R,3R)-1,2,3-trifluoro-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)benzonitrile
Catalogue No.:PA 02 2421007
Molecular Formula : C17H11F4NO3S
Molecular Weight : 385.33
3-Fluoro-5-(((1S,2S,3R)-2-fluoro-1-hydroxy-3-(2-methoxyethoxy)-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)benzonitrile
Catalogue No.:PA 02 2421008
Molecular Formula : C20H19F2NO6S
Molecular Weight : 439.43
Belzutifan-13C-d3
Catalogue No.:PA STI 089698
Molecular Formula : C1613CH9D3F3NO4S
Molecular Weight : 387.35
Belzutifan O-Glucuronide
Catalogue No.:PA 02 2421009
Molecular Formula : C23H20F3NO10S
Molecular Weight : 559.47
3-Fluoro-5-((7-(methylsulfonyl)-2,3-dihydrospiro[indene-1,2'-[1,3]dioxolan]-4-yl)oxy)benzonitrile
Catalogue No.:PA 02 2421010
Molecular Formula : C19H16FNO5S
Molecular Weight : 389.40
3-((3-Bromo-7-(methylsulfonyl)-2,3-dihydrospiro[indene-1,2'-[1,3]dioxolan]-4-yl)oxy)-5-fluorobenzonitrile
Catalogue No.:PA 02 2421011
Molecular Formula : C19H15BrFNO5S
Molecular Weight : 468.29
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