Chemically, it is a derivative of pyrimidine and is only available as the S-enantiomer. Avanafil is a new phosphodiesterase-5 inhibitor that is faster acting and more selective than other drugs belonging to the same class. . Reference standards of Avanafil API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Avanafil
Catalogue No.:PA 28 44000
CAS :
Molecular Formula : C23H26ClN7O3
Molecular Weight : 483.95
(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic Acid
Catalogue No.:PA 28 0441017
Molecular Formula : C18H21ClN4O4
Molecular Weight : 392.84
Avanafil Deschloro Impurity
Catalogue No.:PA 28 44510
Molecular Formula : C23H27N7O3
Molecular Weight : 449.51
Avanafil Amide Analog
Catalogue No.:PA 28 44520
Molecular Formula : C18H22ClN5O3
Molecular Weight : 391.85
Avanafil N-Methyl Analog
Catalogue No.:PA 28 44530
Molecular Formula : C19H24ClN5O3
Molecular Weight : 405.88
Avanafil N-ethyl Analog
Catalogue No.:PA 28 44540
Molecular Formula : C20H26ClN5O3
Molecular Weight : 419.91
Avanafil O-Desmethyl Analog
Catalogue No.:PA 28 44550
Molecular Formula : C22H24ClN7O3
Molecular Weight : 469.92
Avanafil Ethyl Ester Analog
Catalogue No.:PA 28 44560
Molecular Formula : C20H25ClN4O4
Molecular Weight : 420.89
Avanafil Carboxylic Acid Analog
Catalogue No.:PA 28 44570
R-Avanafil
Catalogue No.:PA 28 44580
Avanafil Keto Analog
Catalogue No.:PA 28 44590
Molecular Formula : C18H17ClN6O3
Molecular Weight : 400.82
Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 44600
Molecular Formula : C16H18ClN3O4S
Molecular Weight : 383.85
Avanafi Thiomethyl Analog
Catalogue No.:PA 28 44610
Molecular Formula : C19H19ClN6O2S
Molecular Weight : 430.91
Avanafi Dichloro Analog
Catalogue No.:PA 28 44620
Molecular Formula : C23H25Cl2N7O3
Molecular Weight : 518.4
(1,4,5,6-Tetrahydropyrimidin-2-yl)methanamine
Catalogue No.:PA 28 44630
Molecular Formula : C5H11N3
Molecular Weight : 113.16
4-((4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)amino)-5-hydroxypentanoic Acid
Catalogue No.:PA 28 44640
Molecular Formula : C23H26ClN7O5
Molecular Weight : 515.95
4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic Acid
Catalogue No.:PA 28 44650
Molecular Formula : C14H14ClN3O3S
Molecular Weight : 339.8
Avanafil Isopropyl Amide Analog
Catalogue No.:PA 28 44660
Molecular Formula : C21H28ClN5O3
Molecular Weight : 433.93
Avanafil-13C5,15N
Catalogue No.:PA STI 009310
Molecular Formula : C1813C5H26ClN615NO3
Molecular Weight : 489.91
Avanafil Dimer
Catalogue No.:PA 28 44670
Molecular Formula : C41H45Cl2N11O6
Molecular Weight : 858.78
Ethyl 4-((2-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441000
Molecular Formula : C16H18ClN3O3S
Molecular Weight : 367.85
Ethyl 4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441001
Molecular Formula : C16H17Cl2N3O3S
Molecular Weight : 402.29
Ethyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441002
Molecular Formula : C15H16ClN3O4
Molecular Weight : 337.76
(S)-Ethyl 4-(3-chloro-4-methoxybenzylamino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441004
(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-((1,4,5,6-tetrahydropyrimidin-2-yl)methyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441005
Molecular Formula : C23H30ClN7O3
Molecular Weight : 487.99
(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N,N-bis(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441006
Molecular Formula : C28H30ClN9O3
Molecular Weight : 576.06
(R)-2-(2-(Hydroxymethyl)pyrrolidin-1-yl)-4-((4-methoxybenzyl)amino)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441007
Molecular Weight : 449.52
1H-Benzo[d][1,2,3]triazol-1-yl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441008
Molecular Formula : C24H24ClN7O4
Molecular Weight : 509.95
4-((3-Chloro-4-methoxybenzyl)amino)-2-((S)-2-(((4-((3-chloro-4-methoxybenzyl)amino)-2-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carbonyl)oxy)methyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid
Catalogue No.:PA 28 0441009
Molecular Formula : C36H40Cl2N8O7
Molecular Weight : 767.67
(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-isopropyl-N-(isopropylcarbamoyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441010
Molecular Formula : C25H35ClN6O4
Molecular Weight : 519.04
Ethyl (S)-4-((3,5-dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441011
Molecular Formula : C20H24Cl2N4O4
Molecular Weight : 455.34
(S)-4-((3,5-Dichloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid
Catalogue No.:PA 28 0441012
Molecular Formula : C18H20Cl2N4O4
Molecular Weight : 427.28
Ethyl (S)-4-((2-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441013
4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylsulfinyl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441014
Molecular Formula : C19H19ClN6O3S
Molecular Weight : 446.91
Avanafil D4
Catalogue No.:PA STI 089027
Molecular Formula : C23H22D4ClN7O3
Molecular Weight : 487.98
Avanafil Diamine Impurity
Catalogue No.:PA 28 0441015
Molecular Formula : C26H25Cl2N7O3
Molecular Weight : 554.43
(3,5-Dichloro-4-methoxyphenyl)methanamine Hydrochloride
Catalogue No.:PA 28 0441016
Molecular Formula : C8H10Cl3NO
Molecular Weight : 242.52
4-(Diethylamino)-4'-sulfoazobenzene
Catalogue No.:PA 28 0441018
Molecular Formula : C16H19N3O3S
Molecular Weight : 333.41
(S)-4-((3-Chloro-4-methoxybenzyl)(nitroso)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Catalogue No.:PA 28 0441019
Molecular Formula : C23H25ClN8O4
Molecular Weight : 512.96
(1-(4-((3-Chloro-4-methoxybenzyl)amino)-5-((pyrimidin-2-ylmethyl)carbamoyl)pyrimidin-2-yl)pyrrolidin-2-yl)methyl 4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 28 0441020
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