Aprepitant is used to prevent chemotherapy-induced nausea and vomiting and to prevent postoperative nausea and vomiting.. Reference standards of Aprepitant API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Aprepitant
Catalogue No.:PA 28 07000
CAS :
Molecular Formula : C23H21F7N4O3
Molecular Weight : 534.43
Defluoro Aprepitant
Catalogue No.:PA 28 07010
Molecular Formula : C23H22F6N4O3
Molecular Weight : 516.44
Aprepitant N-Oxide
Catalogue No.:PA 28 07510
Molecular Formula : C23H21F7N4O4
Molecular Weight : 550.43
(R,R,R)-Aprepitant
Catalogue No.:PA 28 07520
ent-Aprepitant
Catalogue No.:PA 28 07550
(R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethan-1-ol
Catalogue No.:PA 28 0071033
Molecular Formula : C10H8F6O
Molecular Weight : 258.16
4-Defluoro-3-(p-fluorophenyl) Aprepitant
Catalogue No.:PA 28 07020
Molecular Formula : C29H25F7N4O3
Molecular Weight : 610.52
4-Defluoro-4-(p-fluorophenyl)aprepitant
Catalogue No.:PA 28 07030
(1R,2S,3S)-Aprepitant
Catalogue No.:PA 28 07530
(1S,2R,3S)-Aprepitant
Catalogue No.:PA 28 07540
(1R,2S,3R)-Aprepitant
Catalogue No.:PA 28 07560
(1S,2R,3R)-Aprepitant
Catalogue No.:PA 28 07570
(1S,2S,3S)-Aprepitant
Catalogue No.:PA 28 07580
Aprepitant M2 Metabolite (1R,2R,3S)-Isomer
Catalogue No.:PA 28 07590
Molecular Formula : C20H18F7NO2
Molecular Weight : 437.35
N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant
Catalogue No.:PA 28 07600
Molecular Formula : C24H25F7N4O4
Molecular Weight : 566.47
ent-Aprepitant-13C15N2
Catalogue No.:PA STI 008250
Molecular Formula : C2213CH21F7N215N2O3
Molecular Weight : 537.40
Aprepitant-13C2,d2 (Major)
Catalogue No.:PA STI 008260
Molecular Formula : C2113C2H19D2F7N4O3
Molecular Weight : 538.42
Aprepitant-d4
Catalogue No.:PA STI 008270
Molecular Formula : C23H17D4F7N4O3
Molecular Weight : 538.45
2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenyl-4-[(2-N- methoxycarbonyl)acetamidrazono]morpholine-13C2,d2
Catalogue No.:PA STI 014030
Molecular Formula : C2213C2H23D2F7N4O4
Molecular Weight : 570.47
2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine-d2 [Aprepitant-M2-d2]
Catalogue No.:PA STI 014040
Molecular Formula : C20H16D2F7NO2
Molecular Weight : 439.36
2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine-d2
Catalogue No.:PA STI 014050
Aprepitant Related Compound A (3-[[(2R,3R)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fl (1041915)
Catalogue No.:PA USP1041915
Molecular Formula : NA
Molecular Weight : NA
Desfluoro Aprepitant (5-{[(2R,3S)-2-{(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-phenylmorpholi (1041992)
Catalogue No.:PA USP1041992
Aprepitant (1041904)
Catalogue No.:PA USP1041904
Aprepitant Related Compound B (3-[[(2S,3R)-2-[(S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fl (1041926)
Catalogue No.:PA USP1041926
Aprepitant (Y0001825)
Catalogue No.:PA EPY0001825
Aprepitant for system suitability (Y0001826)
Catalogue No.:PA EPY0001826
(2R,3S)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine Oxalate
Catalogue No.:PA 28 07610
Molecular Formula : C22H20F7NO6
Molecular Weight : 527.39
N-Methylcarbonyl-2-chloroacetamidrazone
Catalogue No.:PA 28 0071000
Molecular Formula : C4H8ClN3O2
Molecular Weight : 165.58
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate
Catalogue No.:PA 28 0071004
Molecular Formula : C27H26F7NO5S
Molecular Weight : 609.56
Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer
Catalogue No.:PA 28 0071001
Molecular Weight : 437.36
Aprepitant M3 Metabolite (1R, 5R, 6R)-Isomer
Catalogue No.:PA 28 0071002
Molecular Formula : C20H16F7NO3
Molecular Weight : 451.34
Aprepitant M3 Metabolite (1R, 5S, 6R)-Isomer
Catalogue No.:PA 28 0071003
Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'R)-aprepitant
Catalogue No.:PA 28 0071005
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride
Catalogue No.:PA 28 0071006
Molecular Formula : C20H19ClF7NO2
Molecular Weight : 473.82
Aprepitant M2 metabolite (1R, 2R, 3R)-isomer
Catalogue No.:PA 28 0071007
(2R,3R)-2-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine
Catalogue No.:PA 28 0071008
2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine
Catalogue No.:PA 28 0071009
(2S,3S)-2-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine
Catalogue No.:PA 28 0071010
(5R,6S)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)morpholin-3-one
Catalogue No.:PA 28 0071011
(5S,6S)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)morpholin-3-one
Catalogue No.:PA 28 0071012
(5R,6R)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone
Catalogue No.:PA 28 0071013
(5R,6S)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone
Catalogue No.:PA 28 0071014
(5S,6R)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone
Catalogue No.:PA 28 0071015
(5S,6S)-6-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)morpholin-3-one
Catalogue No.:PA 28 0071016
Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-aprepitant
Catalogue No.:PA 28 0071017
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine
Catalogue No.:PA 28 0071018
Molecular Formula : C20H19F6NO2
Molecular Weight : 419.37
2-Chloro-1,3-bis(trifluoromethyl)benzene
Catalogue No.:PA 28 0071019
Molecular Formula : C8H3ClF6
Molecular Weight : 248.55
Aprepitant M2 Metabolite (1R,2R,3R)-Isomer Hydrochloride
Catalogue No.:PA 01 3461000
(R)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine
Catalogue No.:PA 28 0071020
Molecular Formula : C20H16F7NO2
Molecular Weight : 435.34
Aprepitant Glucuronide
Catalogue No.:PA 28 0071021
Molecular Formula : C29H29F7N4O9
Molecular Weight : 710.56
5-(((2S,3S)-3-(4-Fluorophenyl)-2-hydroxymorpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
Catalogue No.:PA 28 0071022
Molecular Formula : C13H15FN4O3
Molecular Weight : 294.29
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine
Catalogue No.:PA 28 0071023
Molecular Formula : C20H17F7N2O3
Molecular Weight : 466.36
(2R)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine
Catalogue No.:PA 28 0071025
(2R,3S)-2-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine
Catalogue No.:PA 28 0071024
4-Benzyl-3-oxomorpholin-2-yl 2,2,2-trifluoroacetate
Catalogue No.:PA 28 0071026
Molecular Formula : C13H12F3NO4
Molecular Weight : 303.24
2,2'-Oxybis(4-benzylmorpholin-3-one)
Catalogue No.:PA 28 0071027
Molecular Formula : C22H24N2O5
Molecular Weight : 396.44
(2R,3R)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine
Catalogue No.:PA 28 0071028
(2S,3S)-2-((S)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine
Catalogue No.:PA 28 0071029
(R)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)morpholin-3-one
Catalogue No.:PA 28 0071030
Molecular Formula : C21H19F6NO3
Molecular Weight : 447.38
(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine Hydrochloride
Catalogue No.:PA 28 0071031
Molecular Formula : C20H20ClF6NO2
Molecular Weight : 455.83
N-Benzyl-N-(2-hydroxyethyl)nitrous amide
Catalogue No.:PA 28 0071032
Molecular Formula : C9H12N2O2
Molecular Weight : 180.21
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