Ambrisentan-Impurities | Pharmaffiliates

ambrisentan and its Impurities

Ambrisentan is a drug indicated for use in the treatment of pulmonary hypertension. Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and European Medicines Agency, and designated an orphan drug, for the treatment of pulmonary hypertension. Reference standards of Ambrisentan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 40 results for ambrisentan Impurities
PA 28 46000

Ambrisentan - API Standards

Ambrisentan


  • Catalogue No.:PA 28 46000

  • CAS :

    177036-94-1

  • Molecular Formula : C22H22N2O4

  • Molecular Weight : 378.42

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PA 28 46510

4,6-Dimethyl-2-(methylsulfonyl)pyrimidine

4,6-Dimethyl-2-(methylsulfonyl)pyrimidine


  • Catalogue No.:PA 28 46510

  • CAS :

    35144-22-0

  • Molecular Formula : C7H10N2O2S

  • Molecular Weight : 186.23

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PA 28 46520

Ambrisentan Hydroxy Acid Impurity

Ambrisentan Hydroxy Acid Impurity (S-Isomer)


  • Catalogue No.:PA 28 46520

  • CAS :

    178306-52-0

  • Molecular Formula : C16H16O4

  • Molecular Weight : 272.3

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PA 28 46540

Ambrisentan Methyl Ester

Ambrisentan Methyl Ester


  • Catalogue No.:PA 28 46540

  • CAS :

    1106685-61-3

  • Molecular Formula : C23H24N2O4

  • Molecular Weight : 392.45

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PA 28 46550

Ambrisentan Vinyloxy Impurity

Ambrisentan Vinyloxy Impurity


  • Catalogue No.:PA 28 46550

  • CAS :

    1639429-81-4

  • Molecular Formula : C20H18N2O

  • Molecular Weight : 302.37

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PA 28 46560

(R)-Ambrisentan

(R)-Ambrisentan


  • Catalogue No.:PA 28 46560

  • CAS :

    1007358-76-0

  • Molecular Formula : C22H22N2O4

  • Molecular Weight : 378.16

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PA 28 46570

3,3-Diphenyl-oxiranecarboxylic Acid Methyl Ester

3,3-Diphenyl-oxiranecarboxylic Acid Methyl Ester


  • Catalogue No.:PA 28 46570

  • CAS :

    76527-25-8

  • Molecular Formula : C16H14O3

  • Molecular Weight : 254.28

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PA 28 46580

2-Hydroxy-4,6-dimethyl Pyrimidine

2-Hydroxy-4,6-dimethyl Pyrimidine


  • Catalogue No.:PA 28 46580

  • CAS :

    108-79-2

  • Molecular Formula : C6H8N2O

  • Molecular Weight : 124.14

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PA 28 46590

rac Ambrisentan

rac Ambrisentan


  • Catalogue No.:PA 28 46590

  • CAS :

    713516-99-5

  • Molecular Formula : C22H22N2O4

  • Molecular Weight : 378.42

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PA 28 0461009

Diphenylacetaldehyde

Diphenylacetaldehyde


  • Catalogue No.:PA 28 0461009

  • CAS :

    947-91-1

  • Molecular Formula : C14H12O

  • Molecular Weight : 196.25

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PA 28 46530

(S)-Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate

(S)-Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate


  • Catalogue No.:PA 28 46530

  • CAS :

    177036-78-1

  • Molecular Formula : C17H18O4

  • Molecular Weight : 286.32

PA STI 005030

rac Ambrisentan-d3

rac Ambrisentan-d3


  • Catalogue No.:PA STI 005030

  • CAS :

    1189479-60-4

  • Molecular Formula : C22H19D3N2O4

  • Molecular Weight : 381.44

PA STI 005031

rac-Ambrisentan-d5

rac-Ambrisentan-d5


  • Catalogue No.:PA STI 005031

  • CAS :

    1392210-85-3

  • Molecular Formula : C22H17D5N2O4

  • Molecular Weight : 383.45

PA STI 005040

rac Ambrisentan-d3 Methyl Ester

rac Ambrisentan-d3 Methyl Ester


  • Catalogue No.:PA STI 005040

  • CAS :

    1329837-75-3

  • Molecular Formula : C23H21D3N2O4

  • Molecular Weight : 395.47

PA STI 033300

4,6-Dimethoxy-β-methyl-3-phenoxy Ambrisentan-d5

4,6-Dimethoxy-β-methyl-3-phenoxy Ambrisentan-d5


  • Catalogue No.:PA STI 033300

  • CAS :

    1346597-40-7

  • Molecular Formula : C22H17D5N2O6

  • Molecular Weight : 415.45

PA STI 049730

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid-d3 Methyl Ester

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid-d3 Methyl Ester


  • Catalogue No.:PA STI 049730

  • CAS :

    1046116-52-2

  • Molecular Formula : C17H15D3O4

  • Molecular Weight : 289.34

PA STI 050030

rac 4-Hydroxymethyl Ambrisentan-d3

rac 4-Hydroxymethyl Ambrisentan-d3


  • Catalogue No.:PA STI 050030

  • CAS :

    1287096-42-7

  • Molecular Formula : C22H19D3N2O5

  • Molecular Weight : 397.44

PAI 01 016010

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid

2-Hydroxy-3-methoxy-3,3-diphenylpropanoic Acid


  • Catalogue No.:PAI 01 016010

  • CAS :

    178306-51-9

  • Molecular Formula : C16H16O4

  • Molecular Weight : 272.30

PAI 01 016020

Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate

Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropanoate


  • Catalogue No.:PAI 01 016020

  • CAS :

    NA

  • Molecular Formula : C17H18O4

  • Molecular Weight : 286.33

PA 28 46600

rac Ambrisentan Methyl Ester

rac Ambrisentan Methyl Ester


  • Catalogue No.:PA 28 46600

  • CAS :

    1240470-84-1

  • Molecular Formula : C23H24N2O4

  • Molecular Weight : 392.45

PA 28 46610

Ambrisentan Acyl β-D-Glucuronide

Ambrisentan Acyl β-D-Glucuronide


  • Catalogue No.:PA 28 46610

  • CAS :

    1106685-58-8

  • Molecular Formula : C28H30N20O10

  • Molecular Weight : 554.55

PA 28 46620

Ambrisentan Pyrimidine Ester Impurity

Ambrisentan Pyrimidine Ester Impurity


  • Catalogue No.:PA 28 46620

  • CAS :

    NA

  • Molecular Formula : C23H24N2O4

  • Molecular Weight : 392.46

PAI 01 016030

Methyl 3-methoxy-2-methyl-3,3-diphenylpropanoate

Methyl 3-methoxy-2-methyl-3,3-diphenylpropanoate


  • Catalogue No.:PAI 01 016030

  • CAS :

    NA

  • Molecular Formula : C18H20O3

  • Molecular Weight : 284.36

PAI 01 016040

3-Methoxy-2-methyl-3,3-diphenylpropanoic Acid

3-Methoxy-2-methyl-3,3-diphenylpropanoic Acid


  • Catalogue No.:PAI 01 016040

  • CAS :

    NA

  • Molecular Formula : C17H18O3

  • Molecular Weight : 270.33

PA 28 0461000

2,3-Dihydroxy-3,3-diphenylpropionic Acid Methyl Ester

2,3-Dihydroxy-3,3-diphenylpropionic Acid Methyl Ester


  • Catalogue No.:PA 28 0461000

  • CAS :

    NA

  • Molecular Formula : C16H16O4

  • Molecular Weight : 272.3

PA 28 0461001

(S)-4-Hydroxymethyl Ambrisentan

(S)-2-((4-(Hydroxymethyl)-6-methylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid


  • Catalogue No.:PA 28 0461001

  • CAS :

    1106685-66-8

  • Molecular Formula : C22H22N2O5

  • Molecular Weight : 394.43

PA 28 0461002

(R,S)-Ambrisentan acyl-β-D-glucuronide

(2S,3S,4S,5R)-6-((2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid


  • Catalogue No.:PA 28 0461002

  • CAS :

    1106685-82-8

  • Molecular Formula : C28H30N2O10

  • Molecular Weight : 554.55

PA 28 0461003

Ambrisentan Hydroxy Acid Impurity (R-Isomer)

(R)-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid


  • Catalogue No.:PA 28 0461003

  • CAS :

    178306-49-5

  • Molecular Formula : C16H16O4

  • Molecular Weight : 272.3

PA 28 0461004

rac 4-Hydroxymethyl Ambrisentan

rac 4-Hydroxymethyl Ambrisentan


  • Catalogue No.:PA 28 0461004

  • CAS :

    1106685-84-0

  • Molecular Formula : C22H22N2O5

  • Molecular Weight : 394.43

PA 28 0461005

Ethyl (S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate

Ethyl (S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoate


  • Catalogue No.:PA 28 0461005

  • CAS :

    1349854-31-4

  • Molecular Formula : C24H26N2O4

  • Molecular Weight : 406.48

PA 28 0461006

2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid ethyl ester

2-[(4,6-Dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenyl propanoic acid ethyl ester


  • Catalogue No.:PA 28 0461006

  • CAS :

    NA

  • Molecular Formula : C24H26N2O4

  • Molecular Weight : 406.48

PA 28 0461007

2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3,3-diphenylacrylic acid

2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3,3-diphenylacrylic acid


  • Catalogue No.:PA 28 0461007

  • CAS :

    1312092-82-2

  • Molecular Formula : C21H18N2O3

  • Molecular Weight : 346.39

PA 28 0461008

Ambrisentan N-Oxide

Ambrisentan N-Oxide


  • Catalogue No.:PA 28 0461008

  • CAS :

    NA

  • Molecular Formula : C22H22N2O5

  • Molecular Weight : 394.43

PA STI 088903

(S)-2-((4-(Hydroxymethyl)-6-(methyl-d3)pyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid

(S)-2-((4-(Hydroxymethyl)-6-(methyl-d3)pyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid


  • Catalogue No.:PA STI 088903

  • CAS :

    NA

  • Molecular Formula : C22H19D3N2O5

  • Molecular Weight : 397.45

PA STI 088904

Ambrisentan D3

Ambrisentan D3


  • Catalogue No.:PA STI 088904

  • CAS :

    1046116-26-0

  • Molecular Formula : C22H19D3N2O4

  • Molecular Weight : 381.45

PAI 01 016041

2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1-phenylethan-1-one

2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1-phenylethan-1-one


  • Catalogue No.:PAI 01 016041

  • CAS :

    2052996-29-7

  • Molecular Formula : C14H14N2O2

  • Molecular Weight : 242.28

PAI 01 016042

2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1,1-diphenylethan-1-ol

2-((4,6-Dimethylpyrimidin-2-yl)oxy)-1,1-diphenylethan-1-ol


  • Catalogue No.:PAI 01 016042

  • CAS :

    2052996-28-6

  • Molecular Formula : C20H20N2O2

  • Molecular Weight : 320.39

PA STI 089231

4-Hydroxymethyl Ambrisentan D5

4-Hydroxymethyl Ambrisentan D5


  • Catalogue No.:PA STI 089231

  • CAS :

    2012598-50-2

  • Molecular Formula : C22H17D5N2O5

  • Molecular Weight : 399.46

PA 28 0461010

Rac O-Demethyl Ambrisentan

Rac O-Demethyl Ambrisentan


  • Catalogue No.:PA 28 0461010

  • CAS :

    1106685-85-1

  • Molecular Formula : C21H20N2O4

  • Molecular Weight : 364.4

PA BSC 04628601

Diphenylacetaldehyde (BSC)

Diphenylacetaldehyde


  • Catalogue No.:PA BSC 04628601

  • CAS :

    947-91-1

  • Molecular Formula : C14H12O

  • Molecular Weight : 196.25