Alvimopan is used to avoid postoperative ileus following small or large bowel resection and accelerates the gastrointestinal recovery period.It is a peripherally acting μ opioid antagonist. Reference standards of Alvimopan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Alvimopan
Catalogue No.:PA 28 13000
CAS :
Molecular Formula : C25H32N2O4
Molecular Weight : 424.53
(R)-Ethyl-2-(2-((methylsulfonyloxy)methyl)-3-phenylpropanamido)acetate
Catalogue No.:PA 28 13510
Molecular Formula : C15H21NO6S
Molecular Weight : 343.4
Ethyl 2-(2-benzyl-3-hydroxypropanamido)acetate
Catalogue No.:PA 28 13520
Molecular Formula : C14H19NO4
Molecular Weight : 265.3
Ethyl 2-(2-benzylprop-2-enamido)acetate
Catalogue No.:PA 28 13530
Molecular Formula : C14H17NO3
Molecular Weight : 247.29
2-[(2S)-2-Benzyl-3-(methanesulfonyloxy) propanamido]acetic Acid
Catalogue No.:PA 28 13540
Molecular Formula : C13H17NO6S
Molecular Weight : 315.34
Ethyl 2-((S)-2-benzyl-3-(benzyloxy) propanamido)acetate
Catalogue No.:PA 28 13550
Molecular Formula : C21H25NO4
Molecular Weight : 355.43
3-((3R,4S)-3,4-Dimethylpiperidin-4-yl)phenol
Catalogue No.:PA 28 13560
Molecular Formula : C13H19NO
Molecular Weight : 205.3
3-((3S,4R)-3,4-Dimethylpiperidin-4-yl)phenol
Catalogue No.:PA 28 13570
3-((3S,4S)-3,4-Dimethylpiperidin-4-yl)phenol
Catalogue No.:PA 28 13580
(R)-1,2,3,6-Tetrahydro-4-(3-isopropoxyphenyl)-1,3-dimethylpyridine
Catalogue No.:PA 28 13590
Molecular Formula : C16H23NO
Molecular Weight : 245.36
(3R,4S)-1,2,3,4-Tetrahydro-4-(3-isopropoxyphenyl)-1,3,4-trimethylpyridine
Catalogue No.:PA 28 13600
Molecular Formula : C17H25NO
Molecular Weight : 259.39
(3R,4R)-Phenyl 4-(3-isopropoxyphenyl)-3,4-dimethylpiperidine-1-carboxylate
Catalogue No.:PA 28 13610
Molecular Formula : C23H29NO3
Molecular Weight : 367.48
2-((R)-2-Benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid
Catalogue No.:PA 28 13620
2-((S)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid
Catalogue No.:PA 28 13630
2-((R)-2-Benzyl-3-((3S,4S)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanamido)acetic Acid
Catalogue No.:PA 28 13640
ADL 08-0011-d5
Catalogue No.:PA STI 004240
Molecular Formula : C23H24D5NO3
Molecular Weight : 372.51
Alvimopan-d5
Catalogue No.:PA STI 004960
Molecular Formula : C25H27D5N2O4
Molecular Weight : 429.56
Alvimopan-d7 Hydrate
Catalogue No.:PA STI 004970
Molecular Formula : C25H27D7N2O5
Molecular Weight : 449.59
N-[(2S)-2-[[(Methylsulfonyl)oxy]methyl]-1-oxo-3-phenylpropyl]-glycine Ethyl Ester
Catalogue No.:PA 28 13650
Molecular Weight : 343.39
(3R,4R)-3-4-Dimethyl-4-(3-hydroxyphenyl) Piperidine
Catalogue No.:PA 28 13660
2-((S)-2-(((3R,4R)-4-(4-Bromo-3-hydroxyphenyl)-3-4-dimethylpiperidin-1-yl)methyl)-3-phenylpropanamido)acetic Acid
Catalogue No.:PA 28 13670
Molecular Formula : C25H31BrN2O4
Molecular Weight : 503.44
ADL 08-0011
Catalogue No.:PA 28 13680
Alvimopan Acyl-β-D-glucuronide
Catalogue No.:PA 28 13690
Molecular Formula : C31H40N2O10
Molecular Weight : 600.66
tert-Butyl 3-Methyl-4-oxopiperidine-1-carboxylate
Catalogue No.:PAI 28 013001
Molecular Formula : C11H19NO3
Molecular Weight : 213.28
tert-Butyl 4-hydroxy-4-(3-methoxyphenyl)-3-methylpiperidine-1-carboxylate
Catalogue No.:PAI 28 013002
Molecular Formula : C18H27NO4
Molecular Weight : 321.42
tert-Butyl 4-bromo-4-(3-methoxyphenyl)-3-methylpiperidine-1-carboxylate
Catalogue No.:PAI 28 013003
Molecular Formula : C18H26BrNO3
Molecular Weight : 384.31
tert-Butyl 4-(3-methoxyphenyl)-3,4-dimethylpiperidine-1-carboxylate
Catalogue No.:PAI 28 013004
Molecular Formula : C19H29NO3
Molecular Weight : 319.45
(alphaS,3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-alpha-(phenylmethyl)-1-piperidinepropanoic acid methyl ester
Catalogue No.:PA 28 0131000
Molecular Formula : C24H31NO3
Molecular Weight : 381.52
N-[1-Oxo-2-(phenylmethyl)-2-propenyl]glycine
Catalogue No.:PA 28 0131001
Molecular Formula : C12H13NO3
Molecular Weight : 219.24
((2S)-2-Benzyl-3-((3R)-4-(3-hydroxyphenyl)-3-methylpiperidin-1-yl)propanoyl)glycine
Catalogue No.:PA 28 0131002
Molecular Formula : C24H36N2O4
Molecular Weight : 416.56
Ethyl ((S)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycinate hydrochloride
Catalogue No.:PA 28 0131003
Molecular Formula : C27H37ClN2O4
Molecular Weight : 489.05
((S)-2-Benzyl-3-((3R,4R)-3,4-dimethyl-4-(3-(sulfooxy)phenyl)piperidin-1-yl)propanoyl)glycine
Catalogue No.:PA 28 0131004
Molecular Formula : C25H32N2O7S
Molecular Weight : 504.6
Methyl (Z)-2-(((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)methyl)-3-phenylacrylate hydrochloride
Catalogue No.:PA 28 0131005
Molecular Formula : C24H30ClNO3
Molecular Weight : 415.96
Ethyl ((S)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycinate
Catalogue No.:PA 28 0131006
Molecular Formula : C27H36N2O4
Molecular Weight : 452.6
3-(1,3,6-Trimethyl-1,2,3,6-tetrahydropyridin-4-yl)phenol
Catalogue No.:PA 28 0131007
Molecular Formula : C14H19NO
Molecular Weight : 217.31
3-(1,3,5-Trimethyl-1,2,3,6-tetrahydropyridin-4-yl)phenol
Catalogue No.:PA 28 0131008
Methyl ((R)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoyl)glycinate
Catalogue No.:PA 28 0131009
Molecular Formula : C26H34N2O4
Molecular Weight : 438.57
Methyl (R)-(2-benzyl-3-hydroxypropanoyl)glycinate
Catalogue No.:PA 28 0131010
Molecular Formula : C13H17NO4
Molecular Weight : 251.28
Alvimopan D7
Catalogue No.:PA STI 088912
Molecular Formula : C25H25D7N2O4
Molecular Weight : 431.58
Alvimopan Desmethyl Impurity
Catalogue No.:PA 28 0131011
Molecular Formula : C24H30N2O4
Molecular Weight : 410.51
Methyl (R)-2-benzyl-3-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)propanoate Hydrochloride
Catalogue No.:PA 28 0131012
Molecular Formula : C24H32ClNO3
Molecular Weight : 417.97
3-(1,3,3-Trimethyl-1,2,3,6-tetrahydropyridin-4-yl)phenol
Catalogue No.:PA 28 0131013
4-(3-Isopropoxyphenyl)-1,3,4-trimethyl-1,2,3,4-tetrahydropyridine
Catalogue No.:PA 28 0131014
Ethyl-2-[(2S)-2-benzyl-3-Hydroxy propanamido]acetate
Catalogue No.:PA 28 0131016
Molecular Weight : 265.31
(S)-2-Benzyl-3-(benzyloxy)propanoic Acid
Catalogue No.:PA 28 0131015
Molecular Formula : C17H18O3
Molecular Weight : 270.33
(3R,4R)-4-(3-Isopropoxyphenyl)-1,3,4-trimethylpiperidine
Catalogue No.:PA 28 0131017
Molecular Formula : C17H27NO
Molecular Weight : 261.41
rel-3-((3R,4S)-3,4-Dimethylpiperidin-4-yl)phenol
Catalogue No.:PA 28 0131018
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