Alogliptin is prepared as a benzoate salt. It is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4, inhibitor that decreases blood sugar similar to the other. Reference standards of Alogliptin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Alogliptin
Catalogue No.:PA 28 43000
CAS :
Molecular Formula : C18H21N5O2
Molecular Weight : 339.39
Alogliptin 6-Chloro Impurity
Catalogue No.:PA 28 43510
Molecular Formula : C13H10ClN3O2
Molecular Weight : 275.69
Alogliptin 6-Chloro N-Desmethyl Impurity
Catalogue No.:PA 28 43520
Molecular Formula : C12H8ClN3O2
Molecular Weight : 261.66
Alogliptin Carbamoyl Impurity
Catalogue No.:PA 28 43530
Molecular Formula : C18H23N5O3
Molecular Weight : 357.41
Alogliptin N-Des(cyanobenzyl) Impurity
Catalogue No.:PA 28 43540
Molecular Formula : C10H17ClN4O2
Molecular Weight : 260.72
Alogliptin N-Formyl Carbamoyl Impurity
Catalogue No.:PA 28 43550
Molecular Formula : C19H23N5O4
Molecular Weight : 385.42
6-Chloro-1',3-dimethyl-2H-[1,4'-bipyrimidine]-2,2',4,6'(1'H,3H,3'H)-tetraone
Catalogue No.:PA 28 43560
Molecular Formula : C10H9ClN4O4
Molecular Weight : 284.66
2-((6-Chloro-1',3-dimethyl-2,2',4,6'-tetraoxo-1',3,4,6'-tetrahydro-2H-[1,4'-bipyrimidin]-3'(2'H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 43570
Molecular Formula : C18H14ClN5O4
Molecular Weight : 399.79
6-(3-Aminopiperidin-1-yl)-3-methylpyrimidine-2,4(1H,3H)-dione
Catalogue No.:PA 28 43580
Molecular Formula : C10H16N4O2
Molecular Weight : 224.26
(R)-2-((3-Aminopiperidin-1-yl)methyl)benzonitrile Dihydrochloride
Catalogue No.:PA 28 43590
Molecular Formula : C13H19Cl2N3
Molecular Weight : 288.22
(R)-6-(3-Aminopiperidin-1-yl)-1',3-dimethyl-2H-[1,4'-bipyrimidine]-2,2',4,6'(1'H,3H,3'H)-tetraone
Catalogue No.:PA 28 43600
Molecular Formula : C15H20N6O4
Molecular Weight : 348.36
(R)-2-((3-Methyl-6-(3-((1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 43610
Molecular Formula : C23H25N7O4
Molecular Weight : 463.49
(R)-2-(((1-(3-(2-Cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)amino)methyl)benzonitrile
Catalogue No.:PA 28 43620
Molecular Formula : C26H26N6O2
Molecular Weight : 454.52
(R)-2-((3-Acetyl-6-(3-aminopiperidin-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 43630
Molecular Formula : C19H21N5O3
Molecular Weight : 367.4
(R)-N-(1-(3-(2-Cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)acetamide
Catalogue No.:PA 28 43640
Molecular Formula : C20H23N5O3
Molecular Weight : 381.43
(R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzoic Acid
Catalogue No.:PA 28 43650
Molecular Formula : C18H22N4O4
Molecular Weight : 358.39
(R)-2-((6-(3-(1,3-Dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 43660
Molecular Formula : C26H23N5O4
Molecular Weight : 469.49
(R)-tert-Butyl (1-(3-(2-cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)carbamate
Catalogue No.:PA 28 43670
Molecular Formula : C23H29N5O4
Molecular Weight : 439.51
(S)-6-(3-Aminopiperidin-1-yl)-3-methylpyrimidine-2,4(1H,3H)-dione
Catalogue No.:PA 28 43680
(R)-3-Aminopiperidine Dihydrochloride
Catalogue No.:PA 28 43690
Molecular Formula : C5H14Cl2N2
Molecular Weight : 173.08
Pyridin-3-amine Hydrochloride
Catalogue No.:PA 28 43700
Molecular Formula : C5H7ClN2
Molecular Weight : 130.58
2-(((4-Chloro-6-oxo-1,6-dihydropyrimidin-2-yl)oxy)methyl)benzonitrile
Catalogue No.:PA 28 43710
2-(Bromomethyl)benzonitrile
Catalogue No.:PA 28 43720
Molecular Formula : C8H6BrN
Molecular Weight : 196.04
Alogliptin-d3
Catalogue No.:PA STI 004850
Molecular Formula : C18H18D3N5O2
Molecular Weight : 342.41
Alogliptin-13C-d3
Catalogue No.:PA STI 004851
Molecular Formula : C1713CH18D3N5O2
Molecular Weight : 343.40
2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-benzonitrile-d3
Catalogue No.:PA STI 019490
Molecular Formula : C13H7D3ClN3O2
Molecular Weight : 278.71
(Z)-[Amino(4-aminophenyl)methylidene]amino 4-chlorobenzoate
Catalogue No.:PA 28 43740
Molecular Formula : C14H12ClN3O2
Molecular Weight : 289.72
6-Chloro-3-methyluracil
Catalogue No.:PA 28 43730
Molecular Formula : C5H5ClN2O2
Molecular Weight : 160.56
N1-(2-Cyanobenzyl)-3-aminopiperidine
Catalogue No.:PA 28 0431000
Molecular Formula : C13H17N3
Molecular Weight : 215.3
2-[[3,4-Dihydro-3-methyl-2,4-dioxo-6-[(3R)-3-piperidinylamino]-1(2H)-pyrimidinyl]methyl]-benzonitrile
Catalogue No.:PA 28 0431001
Molecular Weight : 339.4
N-Demethyl Alogliptin-2,2,2-Trifluoroacetate
Catalogue No.:PA 28 0431002
Molecular Formula : C19H20F3N5O4
Molecular Weight : 439.4
(S)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 0431003
(S)-N-(1-(3-(2-Cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)-N-((2-hydroxyethyl)carbamoyl)benzamide
Catalogue No.:PA 28 0431004
Molecular Formula : C28H30N6O5
Molecular Weight : 530.59
2-((6-Methoxy-3-methyl-2,4-dioxo-3,4-dihydropyrimidine-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 0431005
Molecular Formula : C14H13N3O3
Molecular Weight : 271.28
(S)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile Hydrochloride
Catalogue No.:PA 28 0431006
Molecular Formula : C18H22ClN5O2
Molecular Weight : 375.86
Alogliptin Hydroxy Impurity
Catalogue No.:PA 28 0431007
Molecular Formula : C18H20N4O3
Molecular Weight : 340.38
2-((6-Hydroxy-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 0431008
Molecular Formula : C13H11N3O3
Molecular Weight : 257.25
(S)-N-(1-(3-(2-Cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)benzamide
Catalogue No.:PA 28 0431009
Molecular Formula : C25H25N5O3
Molecular Weight : 443.51
2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 0431010
(R)-2-((3-Methyl-6-(3-(5-methyl-1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 0431011
Molecular Formula : C27H25N5O4
Molecular Weight : 483.53
(R)-3-Aminopiperidine
Catalogue No.:PA 28 0431012
Molecular Formula : C5H12N2
Molecular Weight : 100.17
Tert-butyl (R)-(1-(2-cyanobenzyl)piperidin-3-yl)carbamate
Catalogue No.:PA 28 0431013
Molecular Formula : C18H25N3O2
Molecular Weight : 315.42
(R)-2-((6-(3-(5-methyl-1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 0431015
Molecular Weight : 469.5
(R)-5-methyl-2-(piperidin-3-yl)isoindoline-1,3-dione
Catalogue No.:PA 28 0431014
Molecular Formula : C14H16N2O2
Molecular Weight : 244.29
(R)-4-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 0431016
(R)-3-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 0431017
(R)-2-((Tert-butoxycarbonyl)amino)pentane-1,5-diyl Dimethanesulfonate
Catalogue No.:PA 28 0431018
Molecular Formula : C12H25NO8S2
Molecular Weight : 375.45
2,2'-((1-Methyl-2,4,6-trioxohexahydropyrimidine-5,5-diyl)bis(methylene))dibenzonitrile
Catalogue No.:PA 28 0431019
Molecular Formula : C21H16N4O3
Molecular Weight : 372.38
2-(Bromomethyl)benzamide
Catalogue No.:PA 28 0431020
Molecular Formula : C8H8BrNO
Molecular Weight : 214.06
3-(Bromomethyl)benzamide
Catalogue No.:PA 28 0431021
4-(Bromomethyl)benzamide
Catalogue No.:PA 28 0431022
(R)-N-(3-(2-Cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-(piperidin-3-yl)nitrous amide
Catalogue No.:PA 28 0431023
Molecular Formula : C18H20N6O3
Molecular Weight : 368.4
2-((6-(3-Aminopiperidin-1-yl)-5-hydroxy-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 0431024
Molecular Formula : C18H21N5O3
Molecular Weight : 355.4
tert-Butyl (R)-(1-(3-(2-cyanobenzyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)carbamate
Catalogue No.:PAI 28 043001
Molecular Formula : C22H27N5O4
Molecular Weight : 425.49
2-((3-Acetyl-6-chloro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PAI 28 043002
Molecular Formula : C14H10ClN3O3
Molecular Weight : 303.7
tert-Butyl (R)-(1-(1-acetyl-3-(2-cyanobenzyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)carbamate
Catalogue No.:PAI 28 043003
Molecular Formula : C24H29N5O5
Molecular Weight : 467.53
(R)-2-((6-(3-((Diphenylmethylene)amino)piperidin-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PAI 28 043004
Molecular Formula : C30H27N5O2
Molecular Weight : 489.58
(R)-3-Amino-1-benzylpiperidine Dihydrochloride
Catalogue No.:PA 28 0431025
Molecular Formula : C12H20Cl2N2
Molecular Weight : 263.21
(R)-5-Methyl-2-(1-nitrosopiperidin-3-yl)isoindoline-1,3-dione
Catalogue No.:PA 28 0431026
Molecular Formula : C14H15N3O3
Molecular Weight : 273.29
N-(3-(2-Cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-(piperidin-3-yl)nitrous amide
Catalogue No.:PA 28 0431027
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