Alogliptin is a dipeptidyl peptidase-4 inhibitor that decreases blood sugar similar to the other. It is an oral anti-diabetic drug in the DPP-4 inhibitor class. It does not decrease the risk of heart attack and stroke. Reference standards of Alogliptin Benzoate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Alogliptin Benzoate
Catalogue No.:PA 28 06000
CAS :
Molecular Formula : C25H27N5O4
Molecular Weight : 461.51
(R)-N-(1-(3-(2-cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)-N-((2-hydroxyethyl)carbamoyl)benzamide
Catalogue No.:PA 28 06510
Molecular Formula : C28H30N6O5
Molecular Weight : 530.57
2-(2-Hydroxyethyl)isoindoline-1,3-dione
Catalogue No.:PA 28 06520
Molecular Formula : C10H9NO3
Molecular Weight : 191.18
(S)-2-((6-(3-(1,3-Dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)benzonitrile
Catalogue No.:PA 28 06530
Molecular Formula : C26H23N5O4
Molecular Weight : 469.49
2,2'-((6-Chloro-2,4-dioxopyrimidine-1,3(2H,4H)-diyl)bis(methylene))dibenzonitrile
Catalogue No.:PA 28 06540
Molecular Formula : C20H13ClN4O2
Molecular Weight : 376.8
(R)-2-((6-(3-((3-(2-Cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 06550
Molecular Formula : C31H30N8O4
Molecular Weight : 578.62
(R)-2,2'-((6-(3-Aminopiperidin-1-yl)-2,4-dioxopyrimidine-1,3(2H,4H)-diyl)bis(methylene))dibenzonitrile
Catalogue No.:PA 28 06560
Molecular Formula : C25H24N6O2
Molecular Weight : 440.5
2-(Dibromomethyl)benzonitrile
Catalogue No.:PA 28 06570
Molecular Formula : C8H5Br2N
Molecular Weight : 274.94
Alogliptin Benzoate S-Isomer
Catalogue No.:PA 28 06580
(R)-2-((1-(3-(2-Cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)carbamoyl)benzoic Acid
Catalogue No.:PA 28 06590
Molecular Formula : C26H25N5O5
Molecular Weight : 487.51
(R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzamide
Catalogue No.:PA 28 06600
Molecular Formula : C18H23N5O3
Molecular Weight : 357.41
(R)-2-((6-(3-Aminopiperidin-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 06610
Molecular Formula : C17H19N5O2
Molecular Weight : 325.37
(R)-N-(1-(3-(2-Cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)formamide
Catalogue No.:PA 28 06620
Molecular Formula : C19H21N5O3
Molecular Weight : 367.4
2-((3-Methyl-2,4,6-trioxotetrahydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 06630
Molecular Formula : C13H11N3O3
Molecular Weight : 257.24
2-((6-Chloro-3-ethyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Catalogue No.:PA 28 06640
Molecular Formula : C14H12ClN3O2
Molecular Weight : 289.72
2-((3-Aminopiperidin-1-yl)methyl)benzonitrile
Catalogue No.:PA 28 06650
Molecular Formula : C13H17N3
Molecular Weight : 215.29
(R)-N-(1-(3-(4-Cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)benzamide
Catalogue No.:PA 28 06660
Molecular Formula : C25H25N5O3
Molecular Weight : 443.5
Alogliptin Benzoylamino Impurity
Catalogue No.:PA 28 06680
(R)-3-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile Benzoate
Catalogue No.:PA 28 0061000
Molecular Weight : 461.52
(R)-4-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile Benzoate
Catalogue No.:PA 28 0061001
(R)-N-(3-(2-Cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-(1-(3-(2-cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)nitrous amide
Catalogue No.:PA 28 0061002
Molecular Formula : C31H29N9O5
Molecular Weight : 607.63
2-((3-Methyl-2,4,6-trioxotetrahydropyrimidin-1(2H)-yl)methyl)benzonitrile Benzoate
Catalogue No.:PA 28 0061003
Molecular Formula : C20H17N3O5
Molecular Weight : 379.37
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