Adapalene is marketed by Galderma under the trade names Differin and Adaferin. It is a member of the retinoid drug class that is typically found in topical formulations used for the treatment of acne. It may be used to treat keratosis pilaris as well as other skin conditions as off-label use. Reference standards of Adapalene API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Adapalene
Catalogue No.:PA 01 22000
CAS :
Molecular Formula : C28H28O3
Molecular Weight : 412.53
2,2′-Binaphthalene-6,6′-dicarboxylic Acid
Catalogue No.:PA 01 22010
Molecular Formula : C22H14O4
Molecular Weight : 342.34
6-[3-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)-4- (methyloxy)phenyl]naphthalene-2-carboxylic acid
Catalogue No.:PA 01 22020
Molecular Formula : C28H28O4
Molecular Weight : 428.53
1-(2-Methoxyphenyl)tricyclo[3.3.1.13,7]decane
Catalogue No.:PA 01 22030
Molecular Formula : C17H22O
Molecular Weight : 242.36
1,1'-[4,4'-Bis(Methoxy)biphenyl-3,3'-diyl]bis(tricyclo[3.3.1.13,7]decane)
Catalogue No.:PA 01 22040
Molecular Formula : C34H42O2
Molecular Weight : 482.7
Methyl 6-Bromo-2-napthoate
Catalogue No.:PA 01 22510
Molecular Formula : C12H9BrO2
Molecular Weight : 265.1
Adapalene Methyl Ester
Catalogue No.:PA 01 22520
Molecular Formula : C29H30O3
Molecular Weight : 426.55
Adapalene (1011709)
Catalogue No.:PA USP1011709
Molecular Formula : NA
Molecular Weight : NA
Adapalene Related Compound B (Methyl 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoate) (1011721)
Catalogue No.:PA USP1011721
Adapalene Related Compound A (Methyl 6-bromo-2-naphthoate) (1011710)
Catalogue No.:PA USP1011710
Adapalene Related Compound C (2-(adamant-1-yl)methoxybenzene) (1011732)
Catalogue No.:PA USP1011732
Adapalene Related Compound D (4,4'-dimethoxy-3,3'-di(adamant-1-yl)biphenyl) (1011743)
Catalogue No.:PA USP1011743
Adapalene Related Compound E (2,2'-binaphthyl-6,6'-dicarboxylic acid) (1011754)
Catalogue No.:PA USP1011754
Adapalene (Y0001121)
Catalogue No.:PA EPY0001121
adapalene (1120RB)
Catalogue No.:PA BP1120RB
adapalene impurity standard (1121RB)
Catalogue No.:PA BP1121RB
Adapalene impurity C (Y0001120)
Catalogue No.:PA EPY0001120
Adapalene for peak identification (Y0001119)
Catalogue No.:PA EPY0001119
2-(1-Adamantyl)-4-bromoanisole
Catalogue No.:PA 01 22530
Molecular Formula : C17H21BrO
Molecular Weight : 321.25
Dimethyl [2,2'-binaphthalene]-6,6'-dicarboxylate
Catalogue No.:PAI 01 018010
Molecular Formula : C24H18O4
Molecular Weight : 370.4
6-Bromo-2-naphthalenemethanol
Catalogue No.:PA 01 0221000
Molecular Formula : C11H9BrO
Molecular Weight : 237.10
6-(4-Methoxyphenyl)-2-naphthoic Acid
Catalogue No.:PA 01 0221001
Molecular Formula : C18H14O3
Molecular Weight : 278.31
6-(3-((3r,5r,7r)-Adamantan-1-yl)-4-methoxyphenyl)-1,4-dioxo-1,4-dihydronaphthalene-2-carboxylic Acid
Catalogue No.:PA 01 0221002
Molecular Formula : C28H26O5
Molecular Weight : 442.51
3'-((3r,5r,7r)-Adamantan-1-yl)-4'-methoxy-3-((E)-3-oxoprop-1-en-1-yl)-[1,1'-biphenyl]-4-carbaldehyde
Catalogue No.:PA 01 0221003
Molecular Formula : C27H28O3
Molecular Weight : 400.52
2-(Adamantan-1-yl)-4-bromophenol
Catalogue No.:PA 01 0221004
Molecular Formula : C16H19BrO
Molecular Weight : 307.23
Methyl 6-(3-(3-hydroxyadamantan-1-yl)-4-methoxyphenyl)-2-naphthoate
Catalogue No.:PA 01 0221005
Molecular Formula : C29H30O4
Molecular Weight : 442.56
O-Desmethyl adapalene
Catalogue No.:PA 01 0221006
Molecular Formula : C27H26O3
Molecular Weight : 398.5
Adapalene Acyl-Glucuronide
Catalogue No.:PA 01 0221007
Molecular Formula : C34H36O9
Molecular Weight : 588.65
3-Hydroxy Adapalene methyl ester
Catalogue No.:PA 01 0221008
O-Desmethyl Adapalene-13C6
Catalogue No.:PA 01 0221009
Molecular Formula : C2113C6H26O3
Molecular Weight : 404.46
6-(3-(3-Bromoadamantan-1-yl)-4-methoxyphenyl)-2-naphthoic Acid
Catalogue No.:PAI 01 018011
Molecular Formula : C28H27BrO3
Molecular Weight : 491.43
6-Bromo-2-naphthoic Acid
Catalogue No.:PA 01 0221010
Molecular Formula : C11H7BrO2
Molecular Weight : 251.08
Adapalene Dimer Impurity
Catalogue No.:PA 01 0221011
Molecular Formula : C46H40O6
Molecular Weight : 688.82
6-[(3-Adamantyl-4-Methoxyphenyl)]-2-Naphthoic Acid Ethyl Ester
Catalogue No.:PAI 01 018012
Molecular Formula : C30H32O3
Molecular Weight : 440.58
Ethyl 6-(3-(3-hydroxyadamantan-1-yl)-4-methoxyphenyl)-2-naphthoate
Catalogue No.:PAI 01 018013
Molecular Formula : C30H32O4
Molecular Weight : 456.58
Methyl 6-(4-methoxyphenyl)-2-naphthoate
Catalogue No.:PA 01 0221012
Molecular Formula : C19H16O3
Molecular Weight : 292.33
Methyl 6-(3-((3r,5r,7r)-adamantan-1-yl)-4-hydroxyphenyl)-2-naphthoate
Catalogue No.:PA 01 0221013
4-(6-Methoxynaphthalen-2-yl)benzoic Acid
Catalogue No.:PA 01 0221014
3-(5-Bromo-2-methoxyphenyl)adamantan-1-ol
Catalogue No.:PAI 01 018014
Molecular Formula : C17H21BrO2
Molecular Weight : 337.26
(3-(3-Hydroxyadamantan-1-yl)-4-methoxyphenyl)boronic Acid
Catalogue No.:PAI 01 018015
Molecular Formula : C17H23BO4
Molecular Weight : 302.18
3-(5-Bromo-2-hydroxyphenyl)adamantan-1-ol
Catalogue No.:PAI 01 018016
Molecular Formula : C16H19BrO2
Molecular Weight : 323.23
1-(3-Bromo-2-methoxyphenyl)adamantane
Catalogue No.:PA 01 0221015
Molecular Weight : 321.26
1,3-Bis(5-bromo-2-methoxyphenyl)adamantane
Catalogue No.:PA 01 0221016
Molecular Formula : C24H26Br2O2
Molecular Weight : 506.28
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