acyclovir and its Impurities
Acyclovir is an antiviral drug, used in the treatment of Herpes and AIDS. It is an an orally active acyclic nucleoside. Reference standards of Acyclovir API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Acyclovir Related Compound A (2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl acetate) (1012076)
Acyclovir Related Compound A (2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl acetate) (1012076)
Catalogue No.:PA USP1012076
CAS :
102728-64-3
Molecular Formula : NA
Molecular Weight : NA
Acyclovir Related Compound F (N-[9-[(2-Hydroxyethoxy)methyl]-6-oxo-6,9-dihydro-1H-purin-2-yl]acetam (1012054)
Acyclovir Related Compound F (N-[9-[(2-Hydroxyethoxy)methyl]-6-oxo-6,9-dihydro-1H-purin-2-yl]acetam (1012054)
Catalogue No.:PA USP1012054
CAS :
110104-37-5
Molecular Formula : NA
Molecular Weight : NA
Acyclovir Related Compound G (2-{[2-(Acetylamino)-6-oxo-1,6-dihydro-9H-purin-9-yl]methoxy}ethyl ace (1012087)
Acyclovir Related Compound G (2-{[2-(Acetylamino)-6-oxo-1,6-dihydro-9H-purin-9-yl]methoxy}ethyl ace (1012087)
Catalogue No.:PA USP1012087
CAS :
75128-73-3
Molecular Formula : NA
Molecular Weight : NA
N,N'-(9,9'-((Ethane-1,2-diylbis(oxy))bis(methylene))bis(6-oxo-6,9-dihydro-1H-purine-9,2-diyl))diacetamide
N,N'-(9,9'-((Ethane-1,2-diylbis(oxy))bis(methylene))bis(6-oxo-6,9-dihydro-1H-purine-9,2-diyl))diacetamide
Catalogue No.:PAI 01 002040
CAS :
1417988-85-2
Molecular Formula : C18H20N10O6
Molecular Weight : 472.41
(2,5,7,10-Tetraoxaundecane-1,11-diyl)bis(2-acetamido-9H-purine-9,6-diyl) bis(diphenylcarbamate)
(2,5,7,10-Tetraoxaundecane-1,11-diyl)bis(2-acetamido-9H-purine-9,6-diyl) bis(diphenylcarbamate)
Catalogue No.:PAI 01 002160
CAS :
NA
Molecular Formula : C47H44N12O10
Molecular Weight : 936.93
N-(9-(11-(2-Acetamido-6-hydroxy-1H-purin-9(6H)-yl)-2,5,7,10-tetraoxaundecyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
N-(9-(11-(2-Acetamido-6-hydroxy-1H-purin-9(6H)-yl)-2,5,7,10-tetraoxaundecyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
Catalogue No.:PAI 01 002200
CAS :
NA
Molecular Formula : C21H28N10O8
Molecular Weight : 548.51
9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-((((9-((2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)amino)methyl)amino)-1,9-dihydro-6H-purin-6-one
9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-((((9-((2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)amino)methyl)amino)-1,9-dihydro-6H-purin-6-one
Catalogue No.:PAI 01 002260
CAS :
NA
Molecular Formula : C21H26N10O8
Molecular Weight : 546.5
2-((6-Oxo-2-((((6-oxo-6,9-dihydro-1H-purin-2-yl)amino)methyl)amino)-1,6-dihydro-9H-purin-9-yl)methoxy)ethyl acetate
2-((6-Oxo-2-((((6-oxo-6,9-dihydro-1H-purin-2-yl)amino)methyl)amino)-1,6-dihydro-9H-purin-9-yl)methoxy)ethyl acetate
Catalogue No.:PAI 01 002280
CAS :
NA
Molecular Formula : C16H18N10O5
Molecular Weight : 430.39
9-((2-Hydroxyethoxy)methyl)-2-((((6-oxo-6,9-dihydro-1H-purin-2-yl)amino)methyl)amino)-1,9-dihydro-6H-purin-6-one
9-((2-Hydroxyethoxy)methyl)-2-((((6-oxo-6,9-dihydro-1H-purin-2-yl)amino)methyl)amino)-1,9-dihydro-6H-purin-6-one
Catalogue No.:PAI 01 002290
CAS :
NA
Molecular Formula : C14H16N10O4
Molecular Weight : 388.35
2-((6-Oxo-2-((((6-oxo-6,9-dihydro-1H-purin-2-yl)amino)methyl)amino)-1,6-dihydro-9H-purin-9-yl)methoxy)ethyl (tert-butoxycarbonyl)-L-valinate
2-((6-Oxo-2-((((6-oxo-6,9-dihydro-1H-purin-2-yl)amino)methyl)amino)-1,6-dihydro-9H-purin-9-yl)methoxy)ethyl (tert-butoxycarbonyl)-L-valinate
Catalogue No.:PAI 01 002300
CAS :
NA
Molecular Formula : C24H33N11O7
Molecular Weight : 587.6
(2R,3S,5R)-5-(2-Acetamido-6-(2-(trimethylsilyl)ethoxy)-9H-purin-9-yl)-2-(acetoxymethyl)tetrahydrofuran-3-yl Acetate
(2R,3S,5R)-5-(2-Acetamido-6-(2-(trimethylsilyl)ethoxy)-9H-purin-9-yl)-2-(acetoxymethyl)tetrahydrofuran-3-yl Acetate
Catalogue No.:PAI 01 002320
CAS :
175730-61-7
Molecular Formula : C21H31N5O7Si
Molecular Weight : 493.59
(2R,3S,5R)-5-(2-Amino-6-(2-(trimethylsilyl)ethoxy)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
(2R,3S,5R)-5-(2-Amino-6-(2-(trimethylsilyl)ethoxy)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
Catalogue No.:PAI 01 002330
CAS :
175730-58-2
Molecular Formula : C15H25N5O4Si
Molecular Weight : 367.48
(2R,3S,5R)-5-(2-Fluoro-6-(2-(trimethylsilyl)ethoxy)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
(2R,3S,5R)-5-(2-Fluoro-6-(2-(trimethylsilyl)ethoxy)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
Catalogue No.:PAI 01 002340
CAS :
151900-41-3
Molecular Formula : C15H23FN4O4Si
Molecular Weight : 370.46
(2S,3R,5S)-5-(2-((((9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-(2-(trimethylsilyl)ethoxy)-9H-purin-2-yl)amino)methyl)amino)-6-(2-(trimethylsilyl)ethoxy)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
(2S,3R,5S)-5-(2-((((9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-(2-(trimethylsilyl)ethoxy)-9H-purin-2-yl)amino)methyl)amino)-6-(2-(trimethylsilyl)ethoxy)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
Catalogue No.:PAI 01 002350
CAS :
NA
Molecular Formula : C31H50N10O8Si2
Molecular Weight : 746.97
N-(9-((2-((2-Acetamido-6-oxo-1,6-dihydro-7H-purin-7-yl)methoxy)ethoxy)methyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
N-(9-((2-((2-Acetamido-6-oxo-1,6-dihydro-7H-purin-7-yl)methoxy)ethoxy)methyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
Catalogue No.:PA 01 20810
CAS :
NA
Molecular Formula : C18H20N10O6
Molecular Weight : 472.42