Unoprostone and its Impurities

Unoprostone is a prostaglandin analogue. Its isopropyl ester, unoprostone isopropyl, was marketed under the trade name Rescula for the management of open-angle glaucoma and ocular hypertension. Reference standards of Unoprostone API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.