Lotilaner, sold under the brand name Xdemvy. It is an ectoparasiticide medication. It is an antiparasitic agent used to treat Demodex blepharitis. Reference standards of Lotilaner API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Lotilaner
Catalogue No.:PA 12 2130000
CAS :
Molecular Formula : C20H14Cl3F6N3O3S
Molecular Weight : 596.75
Lotilaner R-Isomer
Catalogue No.:PA 12 2131000
(S)-3-Methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxylic Acid
Catalogue No.:PA 12 2131001
Molecular Formula : C16H9Cl3F3NO3S
Molecular Weight : 458.66
(S)-3-Methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxamide
Catalogue No.:PA 12 2131002
Molecular Formula : C16H10Cl3F3N2O2S
Molecular Weight : 457.67
(S)-3-(5-Bromo-4-methylthiophen-2-yl)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole
Catalogue No.:PA 12 2131003
Molecular Formula : C15H8BrCl3F3NOS
Molecular Weight : 493.54
(R)-3-(5-Bromo-4-methylthiophen-2-yl)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole
Catalogue No.:PA 12 2131004
Methyl (S)-3-methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxylate
Catalogue No.:PA 12 2131005
Molecular Formula : C17H11Cl3F3NO3S
Molecular Weight : 472.68
Methyl (Z)-3-methyl-5-(4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-enoyl)thiophene-2-carboxylate
Catalogue No.:PA 12 2131006
Molecular Formula : C17H10Cl3F3O3S
Methyl (E)-3-methyl-5-(4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-enoyl)thiophene-2-carboxylate
Catalogue No.:PA 12 2131007
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