Binimetinib, also known as Mektovi and ARRY-162. It is used to treat a type of skin cancer.Reference standards of Binimetinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Binimetinib Isomer
Catalogue No.:PA 02 1851000
CAS :
Molecular Formula : C17H15BrF2N4O3
Molecular Weight : 441.23
Binimetinib Cyclized Impurity
Catalogue No.:PA 02 1851001
Molecular Formula : C21H23BrF2N4O4
Molecular Weight : 513.34
Binimetinib
Catalogue No.:PA 02 1850000
Methyl 4-amino-2,3-difluoro-5-nitrobenzoate
Catalogue No.:PA 02 1851002
Molecular Formula : C8H6F2N2O4
Molecular Weight : 232.14
Binimetinib Glucuronide
Catalogue No.:PA 02 1851003
Molecular Formula : C23H23BrF2N4O9
Molecular Weight : 617.36
Binimetinib Dimer Impurity
Catalogue No.:PA 02 1851004
Molecular Formula : C23H17Br2F3N4O3
Molecular Weight : 614.22
Binimetinib Amide Impurity
Catalogue No.:PA 02 1851005
Molecular Formula : C21H23BrF2N4O3
Molecular Weight : 497.34
Binimetinib Methyl Ester Impurity
Catalogue No.:PA 02 1851006
Molecular Formula : C16H12BrF2N3O2
Molecular Weight : 396.19
5-((4-Bromo-2-fluorophenyl)amino)-N'-(5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carbonyl)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carbohydrazide
Catalogue No.:PA 02 1851007
Molecular Formula : C30H20Br2F4N8O2
Molecular Weight : 760.35
N-(2-(Aminooxy)ethoxy)-5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide
Catalogue No.:PA 02 1851008
Molecular Formula : C17H16BrF2N5O3
Molecular Weight : 456.25
N,N'-(Ethane-1,2-diylbis(oxy))bis(5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide)
Catalogue No.:PA 02 1851009
Molecular Formula : C32H24Br2F4N8O4
Molecular Weight : 820.4
1,3-Dioxoisoindolin-2-yl 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate
Catalogue No.:PA 02 1851010
Molecular Formula : C23H13BrF2N4O4
Molecular Weight : 527.28
1-(4-Bromo-2-fluorophenyl)-8-fluoro-5-methyl-1,5-dihydro-3H-imidazo[4',5':4,5]benzo[1,2-c]isoxazol-3-one
Catalogue No.:PA 02 1851011
Molecular Formula : C15H8BrF2N3O2
Molecular Weight : 380.15
Ethyl 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate
Catalogue No.:PA 02 1851012
Molecular Formula : C17H14BrF2N3O2
Molecular Weight : 410.22
N-Desmethyl Binimetinib
Catalogue No.:PA 02 1851013
Molecular Formula : C16H13BrF2N4O3
Molecular Weight : 427.21
Binimetinib-D3
Catalogue No.:PA STI 089454
Molecular Formula : C17H12D3BrF2N4O3
Molecular Weight : 444.25
Binimetinib Acid Nitroso Impurity
Catalogue No.:PA 02 1851014
Molecular Formula : C15H9BrF2N4O3
Molecular Weight : 411.16
Binimetinib Methyl Ester Nitroso Impurity
Catalogue No.:PA 02 1851015
Molecular Formula : C16H11BrF2N4O3
Molecular Weight : 425.19
Binimetinib Nitroso Amide Impurity
Catalogue No.:PA 02 1851016
Molecular Formula : C21H22BrF2N5O4
Molecular Weight : 526.34
5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-N-(2-(vinyloxy)ethoxy)-1H-benzo[d]imidazole-6-carboxamide
Catalogue No.:PA 02 1851017
Molecular Formula : C19H17BrF2N4O3
Molecular Weight : 467.27
Binimetinib Des Ethanediol Impurity
Catalogue No.:PA 02 1851018
Molecular Formula : C15H11BrF2N4O
Molecular Weight : 381.18
Binimetinib Des Bromo Impurity
Catalogue No.:PA 02 1851019
Molecular Formula : C17H16F2N4O3
Molecular Weight : 362.34
4-Fluoro-5-((2-fluorophenyl)amino)-1-methyl-1H-benzo[d]imidazole-6-carboxylic Acid
Catalogue No.:PA 02 1851020
Molecular Formula : C15H11F2N3O2
Molecular Weight : 303.27
4-Fluoro-5-((2-fluorophenyl)amino)-1-methyl-N-(2-(vinyloxy)ethoxy)-1H-benzo[d]imidazole-6-carboxamide
Catalogue No.:PA 02 1851021
Molecular Formula : C19H18F2N4O3
Molecular Weight : 388.37
5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylic Acid
Catalogue No.:PA 02 1851022
Molecular Formula : C15H10BrF2N3O2
Molecular Weight : 382.16
5-((4-Bromo-2-fluorophenyl)amino)-N-(2-ethoxyethoxy)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide
Catalogue No.:PA 02 1851023
Molecular Formula : C19H19BrF2N4O3
Molecular Weight : 469.29
N-Nitroso Binimetinib
Catalogue No.:PA 02 1851024
Molecular Formula : C17H14BrF2N5O4
Molecular Weight : 470.23
Binimetinib Acid Impurity
Catalogue No.:PA 02 1851025
5-(4-Bromo-2-fluorophenyl)-4-fluoro-7-(2-hydroxyethoxy)-1,6-dimethyl-1,5,6,7-tetrahydro-8H-imidazo[4,5-g]quinazolin-8-one
Catalogue No.:PA 02 1851026
2-((5-((4-Bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamido)oxy)ethyl acetate
Catalogue No.:PA 02 1851027
Molecular Formula : C19H17BrF2N4O4
Molecular Weight : 483.27
2,4-Diamino-3-fluoro-5-nitrobenzoic Acid
Catalogue No.:PA 02 1851028
Molecular Formula : C7H6FN3O4
Molecular Weight : 215.14
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