6β naltrexol and its Impurities

6β-Naltrexol was itself investigated as an opioid antagonist, specifically for the treatment of opioid-induced constipation, and was found to be effective and well-tolerated, but was not further pursued. It is a major active metabolite of naltrexone.Reference standards of 6Β Naltrexol API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.