Olaparib-D4

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Catalogue number:	PA STI 089003
Chemical name:	Olaparib-D4
CAS Number:	NA
Category:	stable isotopes,impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	4-(3-(4-(cyclopropane-1-carbonyl-d4)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one;
Molecular form:	C₂₄H₁₉D₄FN₄O₃
Appearance:	White to Off-White Solid
Mol. Weight:	438.5
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Isotope labelled Olaparib is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Olaparib has been shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Recent studies show that Olaparib increases radiosensitivity of a lung tumor xenograft, making it a potential candidate for use in combination with radiotherapy. Potent PARP inhibitor.