CHIR-99021-d4

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Catalogue number:	PA STI 089345
Chemical name:	CHIR-99021-d4
CAS Number:	NA
Alternate CAS Number:	252917-06-9 (Unlabelled)
Category:	stable isotopes
Synonyms:	6-((2-((4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl-1,1,2,2-d4)amino)nicotinonitrile;
Molecular form:	C₂₂H₁₄D₄Cl₂N₈
Appearance:	NA
Mol. Weight:	469.37
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	CHIR-99021-d4 is the deuterized or labeled form of CHIR-99021 Hydrochloride, which is a potent and highly selective inhibitor of glycogen synthase kinases 3 (GSK-3). CHIR-99021 activates glycogen synthesis in CHO-IR cells and in isolated type 1 diabetic rat skeletal muscle. CHIR-99021 has also been shown to induce the reprogramming of murine and human somatic cells into stem cells.