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Catalogue number: PA STI 082570
Chemical name: TH-302-d8

CAS Number:

918632-75-4

Category: stable isotopes,miscellaneous compounds
Synonyms:

N,N'-Bis(2-bromoethyl)phosphorodiamidic Acid-d8 (1-Methyl-2-nitro-1H-imidazol-5-yl)methyl Ester;

Molecular form: C9H8D8Br2N5O4P
Appearance: NA
Mol. Weight: 457.09
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: TH-302-d8 is the isotope labelled analog of TH-302, a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard. Studies have shown that TH-302 treatment exhibited hypoxia-selective cytotoxicity and DNA damage in human cancer cell.

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