Name: Belumosudil - API Standards
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA 27 07050
Chemical name:	Belumosudil
CAS Number:	911417-87-3
Similar Products:	2109704-99-4(Mesylate Salt)
Category:	aromatics,antiviral agents,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	2-[3-[4-(1H-Indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)acetamide; 2-[3-[4-(1H-Indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide; 2-{3-[4-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy}-N-(propan-2-yl)acetamide;
Molecular form:	C₂₆H₂₄N₆O₂
Appearance:	Off-White to Pale Yellow Solid
Mol. Weight:	452.52
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	KD 025 is an inhibitor of Rho-associated protein kinase II (ROCK-II), a serine/threonine kinase that regulates the formation of actin stress fibers and focal adhesions, smooth muscle contraction, and gene expression (1, 2). KD025 has been shown to reduce infarct volume after transient middle cerebral artery occlusion (2).FDA has approved belumosudil (Rezurock) for the treatment of chronic graft-versus-host disease (GVHD).

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Belumosudil - API Standards

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