6-Desacetyl-6-Bromo Palbociclib

In House Impurity

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Catalogue number:	PA 43 06590
Chemical name:	6-Desacetyl-6-Bromo Palbociclib
CAS Number:	851067-56-6
Category:	pharmaceutical standards,Fine Chemicals,intermediates
Synonyms:	6-Bromo-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one;
Molecular form:	C₂₂H₂₆BrN₇O
Appearance:	NA
Mol. Weight:	484.4
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	6-Desacetyl-6-Bromo Palbociclib is an impurity of Palbociclib,(also known as compound number) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Also, it is derived from 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one (B682195), which is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases