Regorafenib

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Catalogue number:	PA 18 49000
Chemical name:	Regorafenib
CAS Number:	755037-03-7
Similar Products:	1019206-88-2(Monohydrate Salt)
Category:	amines,aromatics,heterocycles,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide;4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide;
Molecular form:	C₂₁H₁₅ClF₄N₄O₃
Appearance:	Light Pink Solid
Mol. Weight:	482.82
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	A multikinase inhibitor, Regorafenib is used in the treatment of metastatic colorectal cancer and advanced gastrointestinal stromal tumors. Shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition.