N-Trifluoroacetyl-N-methyl-deacetylcolchicine

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Catalogue number:	PA 03 0741000
Chemical name:	N-Trifluoroacetyl-N-methyl-deacetylcolchicine
CAS Number:	71295-35-7
Category:	enzyme inhibitors,enzyme activators,pharmaceutical standards,impurities,metabolites,Fine Chemicals
Synonyms:	(S)-2,2,2-Trifluoro-N-methyl-N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide;
Molecular form:	C₂₃H₂₄F₃NO₆
Appearance:	Yellow Solid
Mol. Weight:	467.44
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.