Hymenialdisine Analogue

Stock Status : <%stockStatus%>

<%deliveryStatus%>

Catalogue number:	PA 27 0017530
Chemical name:	Hymenialdisine Analogue
CAS Number:	693222-51-4
Category:	miscellaneous compounds
Synonyms:	5-(2-Amino-5-oxo-1,5-dihydroimidazol-4-ylidene)-3,4,5,10-tetrahydro-2H-azepino[3,4-b]indol-1-one;
Molecular form:	C₁₅H₁₃N₅O₂
Appearance:	Light Yellow to Yellow Solid
Mol. Weight:	295.3
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	The indole derivative of Hymenialdisine, a potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. This compound exhibits very potent inhibition of Chk2 activity in the low nanomolar range. Exhibits an increased selectivity for the checkpoint kinases over natural Hymenialdisine.