1-(3-Chlorophenyl)piperazine

EP/BP
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Catalogue number: PAI 20 002511
Chemical name: 1-(3-Chlorophenyl)piperazine

CAS Number:

6640-24-0

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Category: intermediates
Synonyms:

Trazodone Hydrochloride Impurity L (EP/BP); 1-(m-Chlorophenyl)piperazine; 4-(3-Chlorophenyl)piperazine; N-(3-Chlorophenyl)piperazine; N-(m-Chlorophenyl)piperazine; meta-Chlorophenylpiperazine; mCPP;

Molecular form: C10H13ClN2
Appearance: Colourless Oil
Mol. Weight: 196.68
Storage: 2-8°C Refrigerator, Under inert atmosphere
Shipping Conditions: Ambient
Applications: It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone (1,2,3). The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.

1-(3-Chlorophenyl)piperazine

6640-24-0
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