(E)-5-(3-(Dimethylamino)propylidene)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol;

In House Impurity

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Catalogue number:	PA 01 0941001
Chemical name:	(E)-5-(3-(Dimethylamino)propylidene)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol;
CAS Number:	64520-05-4
Category:	impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	NA Amitriptyline metabolite (+/-)-
Molecular form:	C₂₀H₂₃NO
Appearance:	Pale Beige Solid
Mol. Weight:	293.41
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	(5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).