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Catalogue number: PA 18 26000
Chemical name: Rapamycin

CAS Number:

53123-88-9

Category: Fine Chemicals,enzyme inhibitors,pharmaceutical standards,heterocycles,intermediates,chiral standards
Synonyms:

Everolimus - Impurity A (EP/BP); (-)-Rapamycin; Sirolimus; (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12- [(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17, 21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28- tetraene-2,3,10,14,20-pentone;

Molecular form: C51H79NO13
Appearance: White to Pale Yellow Solid
Mol. Weight: 914.17
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: Rapamycin is also known as Sirolimus which is a naturally occurring triene macrolide antibiotic , used to prevent organ transplant rejection and for the treatment of lymphangioleiomyomatosis (LAM). Rapamycin was also initially used as anti fungal agent. It works by inhibiting the activation of T cells and B cells by reducing the production of interleukin-2.

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