Name: Dovitinib - API Standards
Brand: Pharmaffliates
Rating: 3.50 (5 reviews)

Catalogue number:	PA 04 2460000
Chemical name:	Dovitinib
CAS Number:	405169-16-6
Category:	impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	GFKI 258; TK-258; TKI 258; 4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one; 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1,2-dihydroquinolin-2-one; 2(1H)-Quinolinone, 4-amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-;
Molecular form:	C₂₁H₂₁FN₆O
Appearance:	NA
Mol. Weight:	392.44
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Dovitinib is an orally active small molecule that exhibits potent inhibitory activity against multiple RTKs involved in tumor growth and angiogenesis. Preclinical data show that dovitinib works to inhibit multiple kinases associated with different cancers, including acute myeloid leukemia (AML) and multiple myeloma. Chiron currently has three ongoing Phase I clinical trials for dovitinib.

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Dovitinib - API Standards

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