Name: Celastrol
Brand: Pharmaffliates
Rating: 4.50 (5 reviews)

Catalogue number:	PA PHY 003853
Chemical name:	Celastrol
CAS Number:	34157-83-0
Category:	NA
Synonyms:	3-Hydroxy-2-oxo-24-nor-D:A-friedooleana-1(10),3,5,7-tetraen-29-oic Acid; Tripterin; (9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic Acid; (2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic Acid;
Molecular form:	C₂₉H₃₈O₄
Appearance:	Orange Red Solid
Mol. Weight:	450.6
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	An antioxidant natural product which inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression. Used for clinical treatment for rheumatoid arthritis, was demonstrated to have antiangiogenic activity, and be inhibitory against mice tumor growth by a few recent studies. Celastrol also has been shown to have the power to kill tumor cells and can work as an anticarcinogen. Celastrol is also a leptin sensitizer with the potential to reduce weight in obesity (see W499200).

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