Canertinib Dihydrochloride

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Catalogue number:	PA 03 08000
Chemical name:	Canertinib Dihydrochloride
CAS Number:	289499-45-2
Category:	aromatics,chiral standards,enzyme inhibitors,pharmaceutical standards,intermediates,Fine Chemicals,amines,fluorescent labels and indicators
Synonyms:	CI-1033, N-[4-(3-Chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]acrylamide dihydrochloride; N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide dihydrochloride, PD183805
Molecular form:	C₂₄H₂₇Cl₃FN₅O₃
Appearance:	NA
Mol. Weight:	558.86
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Canertinib Dihydrochlorideis an irreversible tyrosine-kinase inhibitor with activity against EGFR HER-2 and ErbB-4 By 2015, Pfizer had discontinued development of the drug. It is an experimental drug candidate for the treatment of cancer. Canertinib Dihydrochloride has been reported as a substrate for OATP1B3.