| Catalogue number: | PA 05 1991044 |
| Chemical name: | Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol |
CAS Number: |
2891774-71-1 |
| Category: | pharmaceutical standards,impurities,Fine Chemicals,Antibody Drug Conjugate |
| Synonyms: | N-((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)-3-(hydroxymethyl)bicyclo[1.1.1]pentane-1-carboxamide; Bicyclo[1.1.1]pentane-1-carboxamide, N-[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-1-yl]-3-(hydroxymethyl)-; N-[(1S,9S)-9-Ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-1-yl]-3-(hydroxymethyl)bicyclo[1.1.1]pentane-1-carboxamide; |
| Molecular form: | C31H30FN3O6 |
| Appearance: | NA |
| Mol. Weight: | 559.59 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol (compound 45) is a camptothecin compound that can inhibit cell proliferation, with an IC50 of 2.92 ng/mL for MDA‑MB‑468 cells. Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol can be used for the research of cancer |
Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol
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