RTI-336

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Catalogue number:	PA 27 0024973
Chemical name:	RTI-336
CAS Number:	204069-50-1
Alternate CAS Number:	236754-02-2 (Freebase)
Category:	miscellaneous compounds
Synonyms:	5-((1R,2R,3S,5S)-3-(4-Chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl)-3-(p-tolyl)isoxazole Hydrochloride;
Molecular form:	C₂₄H₂₆Cl₂N₂O
Appearance:	Pale Beige Solid
Mol. Weight:	429.39
Storage:	2-8°C Refrigerator, Under inert atmosphere
Shipping Conditions:	Ambient
Applications:	RTI-336 is a a phenyltropane cocaine analog that acts selective dopamine reuptake inhibitor (1,2,3). RTI-336 binds to the dopamine transporter with around 20 times the affinity of cocaine but produces relatively mild stimulant effects. RTI-336 is a potential candidate for pharmacotherapy for treating cocaine addiction.