Name: Mithramycin A - API Standards
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA 13 2170000
Chemical name:	Mithramycin A
CAS Number:	18378-89-7
Category:	impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	Plicamycin; Plicatomycin; Aureolic Acid; Mithracin; Mitramycin; (2S,3S)-3-((1S,3S,4R)-3,4-Dihydroxy-1-methoxy-2-oxopentyl)-2-(((2S,4R,5R,6R)-4-(((2S,4R,5S,6R)-4-(((2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,4R,5R,6R)-4-(((2S,4R,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8,9-dihydroxy-7-methyl-3,4-dihydroanthracen-1(2H)-one;
Molecular form:	C₅₂H₇₆O₂₄
Appearance:	Yellow Solid
Mol. Weight:	1085.16
Storage:	2-8°C Refrigerator, Under inert atmosphere
Shipping Conditions:	Ambient
Applications:	Mithramycin A is an anticancer antibiotic that selectively binds to G-C-rich DNA in the presence of Mg2+ or Zn2+, inhibiting RNA and DNA polymerase action. Mithramycin A inhibits c-myc expression and induces myeloid differentiation of HL-60 promyelocytic leukemia cells.

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