Necrosulfonamide-d4

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Catalogue number:	PA STI 067170
Chemical name:	Necrosulfonamide-d4
CAS Number:	1795144-22-7
Category:	aromatics,heterocycles,stable isotopes,pharmaceutical standards,intermediates,Fine Chemicals,protein kinase inhibitors and activators
Synonyms:	N-[4-[[(3-Methoxypyrazinyl)amino]sulfonyl](phenyl]-d4)-3-(5-nitro-2-thienyl)-2-propenamide; (E)-N-[4-[N-(3-methoxypyrazin-2-yl)sulfamoyl](phenyl-d4)]-3-(5-nitrothiophene-2-yl)acrylamide;
Molecular form:	C₁₈H₁₁D₄N₅O₆S₂
Appearance:	Pale Yellow Solid
Mol. Weight:	465.50
Storage:	2-8°C Amber Vial, Refrigerator, Under Inert Atmosphere
Shipping Conditions:	Ambient
Applications:	Labelled Necrosulfonamide. Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway.