NO-Aspirin 1

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Catalogue number:	PA 27 0017548
Chemical name:	NO-Aspirin 1
CAS Number:	175033-36-0
Category:	miscellaneous compounds
Synonyms:	2-Acetyloxybenzoic Acid 3-Nitrooxymethylphenyl Ester;
Molecular form:	C₁₆H₁₃NO₇
Appearance:	White to Off-White Solid
Mol. Weight:	331.28
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	NO-Aspirin 1 is a hybrid molecule of aspirin and a nitric oxide (NO) donor. It contains an ester linkage, that when cleaved by esterases in the gut, liver, and plasma releases salicylate and an NO-releasing moiety. It also prevents restinosiis, inhibits proliferation of vascular smooth muscle cells, reduces infarct ssize following cardiac ischemia, and exhibits strong chemopreventative effects against colon cancer development.