Combretastatin A4 Phosphate Disodium Salt

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Catalogue number:	PA PHY 004883
Chemical name:	Combretastatin A4 Phosphate Disodium Salt
CAS Number:	168555-66-6
Alternate CAS Number:	222030-63-9 (Free Acid)
Category:	NA
Synonyms:	Disodium,[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] phosphate;
Molecular form:	C₁₈H₁₉Na₂O₈P
Appearance:	White to Off-White Solid
Mol. Weight:	440.3
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Phosphorylated Combretastatin, a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage. A potent cytotoxic agent which strongly inhibits the polymerization of tubulin by binding to the colchicine site.