Hydroxyfasudil

In House Impurity

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Catalogue number:	PA 33 0331000
Chemical name:	Hydroxyfasudil
CAS Number:	155558-32-0
Alternate CAS Number:	105628-72-6 (Free Base)
Category:	impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	5-((1,4-Diazepan-1-yl)sulfonyl)isoquinolin-1-ol hydrochloride;
Molecular form:	C₁₄H₁₈ClN₃O₃S
Appearance:	White to Off-White Solid
Mol. Weight:	343.83
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo.